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- W2019345099 abstract "We report the synthesis of S-nitrosothiol-modified silica particles capable of nitric oxide (NO) release. The thiol precursor modification to form S-nitrosothiol NO donors was introduced into the silica network via co-condensation of mercaptosilane and alkoxysilane precursors. Both the concentration of reactants (i.e., water, ammonia, and silane) and the silane feed rate into the reaction proved important in the yield of monodisperse, spherical particles with tunable diameters ranging from 241−718 nm. Subsequent nitrosation resulted in NO storage approaching ∼4.40 μmol NO mg−1, as determined by total NO release. Behaving similar to low molecular weight S-nitrosothiol NO donors, the NO release from the macromolecular silica vehicles was influenced by light, temperature, and metal ions." @default.
- W2019345099 created "2016-06-24" @default.
- W2019345099 creator A5019721397 @default.
- W2019345099 creator A5028486659 @default.
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- W2019345099 date "2011-03-07" @default.
- W2019345099 modified "2023-09-27" @default.
- W2019345099 title "Stöber Synthesis of Nitric Oxide-Releasing <i>S</i>-Nitrosothiol-Modified Silica Particles" @default.
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- W2019345099 doi "https://doi.org/10.1021/cm102510q" @default.
- W2019345099 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3075092" @default.
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