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• W2019367167 endingPage "67" @default.
• W2019367167 startingPage "54" @default.
• W2019367167 abstract "Stress sensitivity may be one process that can explain why some genetically at-risk individuals are more susceptible to some types of stress-reactive psychopathologies. Dysregulation of the limbic-hypothalamic-pituitary-adrenal (LHPA) axis, including cortisol reactivity to challenge, represents a key aspect of stress sensitivity. However, the degree of stability over time among youth, especially differential stability as a function of particular genetic variants, has not been investigated. A general community sample of children and adolescents (mean age = 11.4; 56% girls) provided a DNA sample and completed 2 separate laboratory stress challenges, across an 18-month follow-up (N = 224 at Time 1; N = 194 at Time 2), with repeated measures of salivary cortisol. Results showed that test-retest stability for several indices of cortisol reactivity across the laboratory challenge visits were significant and of moderate magnitude for the whole sample. Moreover, gene variants of several biologically plausible systems relevant for stress sensitivity (especially 5-HTTLPR and CRHR1) demonstrated differential stability of cortisol reactivity over 18-months, such that carriers of genotypes conferring enhanced environmental susceptibility exhibited greater stability of cortisol levels over time for some LHPA axis indices. Findings suggest that LHPA axis dysregulation may exhibit some trait-like aspects underlying stress sensitivity in youth, especially for those who carry genes related to greater genetic susceptibility to environmental stress." @default.
• W2019367167 created "2016-06-24" @default.
• W2019367167 creator A5007167486 @default.
• W2019367167 creator A5061632541 @default.
• W2019367167 creator A5075818294 @default.
• W2019367167 creator A5085447170 @default.
• W2019367167 date "2015-02-01" @default.
• W2019367167 modified "2023-10-16" @default.
• W2019367167 title "Cortisol reactivity to stress among youth: Stability over time and genetic variants for stress sensitivity." @default.
• W2019367167 cites W1881281756 @default.
• W2019367167 cites W1882787745 @default.
• W2019367167 cites W1938076416 @default.
• W2019367167 cites W1964751586 @default.
• W2019367167 cites W1969625130 @default.
• W2019367167 cites W1970565661 @default.
• W2019367167 cites W1971228815 @default.
• W2019367167 cites W1975042923 @default.
• W2019367167 cites W1976790902 @default.
• W2019367167 cites W1978974103 @default.
• W2019367167 cites W1981559145 @default.
• W2019367167 cites W1982835526 @default.
• W2019367167 cites W1987375729 @default.
• W2019367167 cites W1991161864 @default.
• W2019367167 cites W1992226320 @default.
• W2019367167 cites W1994628299 @default.
• W2019367167 cites W1996480425 @default.
• W2019367167 cites W1999682854 @default.
• W2019367167 cites W2002395285 @default.
• W2019367167 cites W2004539531 @default.
• W2019367167 cites W2004920788 @default.
• W2019367167 cites W2012656447 @default.
• W2019367167 cites W2014534739 @default.
• W2019367167 cites W2016124588 @default.
• W2019367167 cites W2022032719 @default.
• W2019367167 cites W2024158767 @default.
• W2019367167 cites W2027860285 @default.
• W2019367167 cites W2031415599 @default.
• W2019367167 cites W2035403666 @default.
• W2019367167 cites W2038133548 @default.
• W2019367167 cites W2038705308 @default.
• W2019367167 cites W2057881388 @default.
• W2019367167 cites W2059646524 @default.
• W2019367167 cites W2060959954 @default.
• W2019367167 cites W2062999268 @default.
• W2019367167 cites W2063022574 @default.
• W2019367167 cites W2065720089 @default.
• W2019367167 cites W2066405914 @default.
• W2019367167 cites W2067664488 @default.
• W2019367167 cites W2070259385 @default.
• W2019367167 cites W2071760747 @default.
• W2019367167 cites W2075424733 @default.
• W2019367167 cites W2084764358 @default.
• W2019367167 cites W2086628232 @default.
• W2019367167 cites W2086682458 @default.
• W2019367167 cites W2088068432 @default.
• W2019367167 cites W2088525127 @default.
• W2019367167 cites W2091413411 @default.
• W2019367167 cites W2092281603 @default.
• W2019367167 cites W2095149094 @default.
• W2019367167 cites W2096838333 @default.
• W2019367167 cites W2096937728 @default.
• W2019367167 cites W2097974105 @default.
• W2019367167 cites W2098615840 @default.
• W2019367167 cites W2098767958 @default.
• W2019367167 cites W2100230238 @default.
• W2019367167 cites W2102054065 @default.
• W2019367167 cites W2102581653 @default.
• W2019367167 cites W2103768332 @default.
• W2019367167 cites W2104292214 @default.
• W2019367167 cites W2113746812 @default.
• W2019367167 cites W2115871268 @default.
• W2019367167 cites W2120070650 @default.
• W2019367167 cites W2121488984 @default.
• W2019367167 cites W2124408454 @default.
• W2019367167 cites W2127779688 @default.
• W2019367167 cites W2128337375 @default.
• W2019367167 cites W2129282166 @default.
• W2019367167 cites W2135057249 @default.
• W2019367167 cites W2136996580 @default.
• W2019367167 cites W2139383973 @default.
• W2019367167 cites W2140289027 @default.
• W2019367167 cites W2141709307 @default.
• W2019367167 cites W2143780403 @default.
• W2019367167 cites W2145819353 @default.
• W2019367167 cites W2146738944 @default.
• W2019367167 cites W2146759661 @default.
• W2019367167 cites W2150028050 @default.
• W2019367167 cites W2150288466 @default.
• W2019367167 cites W2151579468 @default.
• W2019367167 cites W2153197848 @default.
• W2019367167 cites W2155128807 @default.
• W2019367167 cites W2156683303 @default.
• W2019367167 cites W2156824222 @default.
• W2019367167 cites W2160251605 @default.
• W2019367167 cites W2161085199 @default.
• W2019367167 cites W2166510636 @default.
• W2019367167 cites W2171097731 @default.
• W2019367167 doi "https://doi.org/10.1037/abn0000030" @default.

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