Matches in SemOpenAlex for { <https://semopenalex.org/work/W2019367624> ?p ?o ?g. }
Showing items 1 to 79 of
79
with 100 items per page.
- W2019367624 endingPage "134" @default.
- W2019367624 startingPage "131" @default.
- W2019367624 abstract "The crystal structures of the DNA-N6-adenine-methyltransferase M·TaqI, in complexes with the cofactor S-adenosyl-l-methionine (AdoMet) and the competitive inhibitor sinefungin (Sf) show identical folding of the polypeptide chains into two domains. The N-terminal domain carries the cofactor-binding site, the C-terminal domain is thought to be implicated in sequence-specific DNA binding. Model building of the M·TaqI-DNA complex suggests that the adenine to be methylated swings out of the double helix as found previously in the cytosine-C5-MTase HhaI DNA co-crystal structure. A torsion of the methionine moiety of the cofactor is required to bring the methyl group within reach of the swung-out base and allow methyl group transfer." @default.
- W2019367624 created "2016-06-24" @default.
- W2019367624 creator A5002096304 @default.
- W2019367624 creator A5023894720 @default.
- W2019367624 creator A5034685306 @default.
- W2019367624 creator A5044758922 @default.
- W2019367624 creator A5067698818 @default.
- W2019367624 date "1995-05-01" @default.
- W2019367624 modified "2023-09-29" @default.
- W2019367624 title "A model for DNA binding and enzyme action derived from crystallographic studies of the TaqI N6-adenine-methyltransferase" @default.
- W2019367624 cites W1527255186 @default.
- W2019367624 cites W2008000048 @default.
- W2019367624 cites W2017249715 @default.
- W2019367624 cites W2033625455 @default.
- W2019367624 cites W2053655118 @default.
- W2019367624 cites W2076909297 @default.
- W2019367624 cites W2076911571 @default.
- W2019367624 cites W2077890483 @default.
- W2019367624 cites W2141221250 @default.
- W2019367624 doi "https://doi.org/10.1016/0378-1119(94)00690-t" @default.
- W2019367624 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7607476" @default.
- W2019367624 hasPublicationYear "1995" @default.
- W2019367624 type Work @default.
- W2019367624 sameAs 2019367624 @default.
- W2019367624 citedByCount "33" @default.
- W2019367624 countsByYear W20193676242017 @default.
- W2019367624 countsByYear W20193676242023 @default.
- W2019367624 crossrefType "journal-article" @default.
- W2019367624 hasAuthorship W2019367624A5002096304 @default.
- W2019367624 hasAuthorship W2019367624A5023894720 @default.
- W2019367624 hasAuthorship W2019367624A5034685306 @default.
- W2019367624 hasAuthorship W2019367624A5044758922 @default.
- W2019367624 hasAuthorship W2019367624A5067698818 @default.
- W2019367624 hasConcept C107824862 @default.
- W2019367624 hasConcept C181199279 @default.
- W2019367624 hasConcept C185592680 @default.
- W2019367624 hasConcept C197957613 @default.
- W2019367624 hasConcept C2776023528 @default.
- W2019367624 hasConcept C2779979206 @default.
- W2019367624 hasConcept C33288867 @default.
- W2019367624 hasConcept C552990157 @default.
- W2019367624 hasConcept C55493867 @default.
- W2019367624 hasConcept C71240020 @default.
- W2019367624 hasConcept C86803240 @default.
- W2019367624 hasConcept C91965660 @default.
- W2019367624 hasConceptScore W2019367624C107824862 @default.
- W2019367624 hasConceptScore W2019367624C181199279 @default.
- W2019367624 hasConceptScore W2019367624C185592680 @default.
- W2019367624 hasConceptScore W2019367624C197957613 @default.
- W2019367624 hasConceptScore W2019367624C2776023528 @default.
- W2019367624 hasConceptScore W2019367624C2779979206 @default.
- W2019367624 hasConceptScore W2019367624C33288867 @default.
- W2019367624 hasConceptScore W2019367624C552990157 @default.
- W2019367624 hasConceptScore W2019367624C55493867 @default.
- W2019367624 hasConceptScore W2019367624C71240020 @default.
- W2019367624 hasConceptScore W2019367624C86803240 @default.
- W2019367624 hasConceptScore W2019367624C91965660 @default.
- W2019367624 hasIssue "1-2" @default.
- W2019367624 hasLocation W20193676241 @default.
- W2019367624 hasLocation W20193676242 @default.
- W2019367624 hasOpenAccess W2019367624 @default.
- W2019367624 hasPrimaryLocation W20193676241 @default.
- W2019367624 hasRelatedWork W2002788005 @default.
- W2019367624 hasRelatedWork W2017191738 @default.
- W2019367624 hasRelatedWork W2019492821 @default.
- W2019367624 hasRelatedWork W2055728251 @default.
- W2019367624 hasRelatedWork W2059346522 @default.
- W2019367624 hasRelatedWork W2070073322 @default.
- W2019367624 hasRelatedWork W2081535035 @default.
- W2019367624 hasRelatedWork W2400132286 @default.
- W2019367624 hasRelatedWork W2537181816 @default.
- W2019367624 hasRelatedWork W3131469594 @default.
- W2019367624 hasVolume "157" @default.
- W2019367624 isParatext "false" @default.
- W2019367624 isRetracted "false" @default.
- W2019367624 magId "2019367624" @default.
- W2019367624 workType "article" @default.