FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2019392790> ?p ?o ?g. }

• W2019392790 endingPage "302" @default.
• W2019392790 startingPage "297" @default.
• W2019392790 abstract "The ATP-binding cassette transporter A1 (ABCA1) is an important effector in the regulation of cholesterol efflux from cells. In this study, we assessed the role of ABCA1 in human carotid atherosclerotic plaques (CAPs). We found that ABCA1 and retinoid X receptor α (RXRα) mRNAs were significantly increased in the atherosclerotic plaques compared to control arteries. The increased ABCA1 mRNA correlated with that of RXRα in plaques. According to the modified American Heart Association plaque classification, atherosclerotic specimens were assigned to three grades, and ABCA1 and RXRα mRNA levels were compared across plaques of different grades. Resultantly, plaques of grade II and III exhibited higher mRNA levels than grade I, but there was no difference in mRNA levels between plaques of grade II and III. By contrast, ABCA1 and RXRα protein levels were notably reduced in plaques relative to control tissues. Similarly, plaques of grade II and III exhibited lower ABCA1 and RXRα protein levels than grade I, and there was no difference in protein levels between plaques of grade II and III. Our findings suggest that decreased ABCA1 protein plays a key role in the pathogenesis of CAP; the regulation of ABCA1 may be mediated by RXRα and ABCA1 mRNA levels may serve as an indicator for plaque stability." @default.
• W2019392790 created "2016-06-24" @default.
• W2019392790 creator A5020334188 @default.
• W2019392790 creator A5034223608 @default.
• W2019392790 creator A5053204257 @default.
• W2019392790 creator A5054063853 @default.
• W2019392790 creator A5062701102 @default.
• W2019392790 creator A5069942317 @default.
• W2019392790 creator A5074808340 @default.
• W2019392790 date "2012-05-15" @default.
• W2019392790 modified "2023-09-28" @default.
• W2019392790 title "Significance of ABCA1 in human carotid atherosclerotic plaques" @default.
• W2019392790 cites W1570388980 @default.
• W2019392790 cites W1607399348 @default.
• W2019392790 cites W18060272 @default.
• W2019392790 cites W1970329005 @default.
• W2019392790 cites W1986439388 @default.
• W2019392790 cites W1987556693 @default.
• W2019392790 cites W1991691591 @default.
• W2019392790 cites W2004168108 @default.
• W2019392790 cites W2022377893 @default.
• W2019392790 cites W2039855201 @default.
• W2019392790 cites W2046493105 @default.
• W2019392790 cites W2048397414 @default.
• W2019392790 cites W2053365325 @default.
• W2019392790 cites W2056452930 @default.
• W2019392790 cites W2086317930 @default.
• W2019392790 cites W2092461792 @default.
• W2019392790 cites W2097583089 @default.
• W2019392790 cites W2099632438 @default.
• W2019392790 cites W2126338779 @default.
• W2019392790 cites W2128738849 @default.
• W2019392790 cites W2157283676 @default.
• W2019392790 cites W2159263105 @default.
• W2019392790 cites W2161682643 @default.
• W2019392790 cites W2168300371 @default.
• W2019392790 cites W2177869932 @default.
• W2019392790 cites W4256317085 @default.
• W2019392790 doi "https://doi.org/10.3892/etm.2012.576" @default.
• W2019392790 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3439128" @default.
• W2019392790 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22970033" @default.
• W2019392790 hasPublicationYear "2012" @default.
• W2019392790 type Work @default.
• W2019392790 sameAs 2019392790 @default.
• W2019392790 citedByCount "20" @default.
• W2019392790 countsByYear W20193927902014 @default.
• W2019392790 countsByYear W20193927902015 @default.
• W2019392790 countsByYear W20193927902016 @default.
• W2019392790 countsByYear W20193927902018 @default.
• W2019392790 countsByYear W20193927902019 @default.
• W2019392790 countsByYear W20193927902021 @default.
• W2019392790 countsByYear W20193927902022 @default.
• W2019392790 crossrefType "journal-article" @default.
• W2019392790 hasAuthorship W2019392790A5020334188 @default.
• W2019392790 hasAuthorship W2019392790A5034223608 @default.
• W2019392790 hasAuthorship W2019392790A5053204257 @default.
• W2019392790 hasAuthorship W2019392790A5054063853 @default.
• W2019392790 hasAuthorship W2019392790A5062701102 @default.
• W2019392790 hasAuthorship W2019392790A5069942317 @default.
• W2019392790 hasAuthorship W2019392790A5074808340 @default.
• W2019392790 hasBestOaLocation W20193927901 @default.
• W2019392790 hasConcept C104317684 @default.
• W2019392790 hasConcept C105580179 @default.
• W2019392790 hasConcept C126322002 @default.
• W2019392790 hasConcept C128821507 @default.
• W2019392790 hasConcept C134018914 @default.
• W2019392790 hasConcept C142724271 @default.
• W2019392790 hasConcept C149011108 @default.
• W2019392790 hasConcept C190283241 @default.
• W2019392790 hasConcept C2777704780 @default.
• W2019392790 hasConcept C2778163477 @default.
• W2019392790 hasConcept C2780942790 @default.
• W2019392790 hasConcept C2781018059 @default.
• W2019392790 hasConcept C29537977 @default.
• W2019392790 hasConcept C55493867 @default.
• W2019392790 hasConcept C63932345 @default.
• W2019392790 hasConcept C71924100 @default.
• W2019392790 hasConcept C86339819 @default.
• W2019392790 hasConcept C86803240 @default.
• W2019392790 hasConceptScore W2019392790C104317684 @default.
• W2019392790 hasConceptScore W2019392790C105580179 @default.
• W2019392790 hasConceptScore W2019392790C126322002 @default.
• W2019392790 hasConceptScore W2019392790C128821507 @default.
• W2019392790 hasConceptScore W2019392790C134018914 @default.
• W2019392790 hasConceptScore W2019392790C142724271 @default.
• W2019392790 hasConceptScore W2019392790C149011108 @default.
• W2019392790 hasConceptScore W2019392790C190283241 @default.
• W2019392790 hasConceptScore W2019392790C2777704780 @default.
• W2019392790 hasConceptScore W2019392790C2778163477 @default.
• W2019392790 hasConceptScore W2019392790C2780942790 @default.
• W2019392790 hasConceptScore W2019392790C2781018059 @default.
• W2019392790 hasConceptScore W2019392790C29537977 @default.
• W2019392790 hasConceptScore W2019392790C55493867 @default.
• W2019392790 hasConceptScore W2019392790C63932345 @default.
• W2019392790 hasConceptScore W2019392790C71924100 @default.
• W2019392790 hasConceptScore W2019392790C86339819 @default.
• W2019392790 hasConceptScore W2019392790C86803240 @default.
• W2019392790 hasIssue "2" @default.

• next