Matches in SemOpenAlex for { <https://semopenalex.org/work/W2019397458> ?p ?o ?g. }
Showing items 1 to 87 of
87
with 100 items per page.
- W2019397458 endingPage "230" @default.
- W2019397458 startingPage "220" @default.
- W2019397458 abstract "Infections of avian embryos with Plasmodium gallinaceum from a malaria strain adapted to continuous passage in chicks were characterized by reduced virulence. Five passages through embryos were required to produce infections comparable to those observed in established infections. If blood from a chicken infected by sporozoites was injected into 10-day chicken embryos there were a marked loss of virulence, heightened pathogenicity, and morphological aberrations. Increasing the dosage from a million to 20 × 10 6 parasites resulted in parasitemias more nearly resembling those in fully adapted passages in chicken embryos. Blood passages from chicken to chicken somehow changed the parasite to the point that after four passages acute virulent infections could be obtained in the embryo. It is postulated that the chicken embryo by virtue of its difference from neonates as regards plasma elements and physiochemical composition of its erythrocytes, especially in the hemoglobin, constitutes essentially a foreign host to which a few parasites are preadapted. During blood passages selection toward virulence ensues." @default.
- W2019397458 created "2016-06-24" @default.
- W2019397458 creator A5021224834 @default.
- W2019397458 creator A5074112997 @default.
- W2019397458 creator A5089278575 @default.
- W2019397458 date "1977-10-01" @default.
- W2019397458 modified "2023-09-27" @default.
- W2019397458 title "Plasmodium gallinaceum: Changing virulence patterns of malaria parasites during adaptation from neonate chick to chicken embryos" @default.
- W2019397458 cites W1991011877 @default.
- W2019397458 cites W2014260414 @default.
- W2019397458 cites W2046414350 @default.
- W2019397458 cites W2059148896 @default.
- W2019397458 cites W2074152516 @default.
- W2019397458 cites W2074236257 @default.
- W2019397458 cites W2089981850 @default.
- W2019397458 cites W2167635748 @default.
- W2019397458 cites W2171886415 @default.
- W2019397458 cites W2267870166 @default.
- W2019397458 cites W2321524613 @default.
- W2019397458 cites W2322500502 @default.
- W2019397458 cites W2329950462 @default.
- W2019397458 doi "https://doi.org/10.1016/0014-4894(77)90026-1" @default.
- W2019397458 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/891706" @default.
- W2019397458 hasPublicationYear "1977" @default.
- W2019397458 type Work @default.
- W2019397458 sameAs 2019397458 @default.
- W2019397458 citedByCount "5" @default.
- W2019397458 crossrefType "journal-article" @default.
- W2019397458 hasAuthorship W2019397458A5021224834 @default.
- W2019397458 hasAuthorship W2019397458A5074112997 @default.
- W2019397458 hasAuthorship W2019397458A5089278575 @default.
- W2019397458 hasConcept C104317684 @default.
- W2019397458 hasConcept C136764020 @default.
- W2019397458 hasConcept C159047783 @default.
- W2019397458 hasConcept C196843134 @default.
- W2019397458 hasConcept C203014093 @default.
- W2019397458 hasConcept C2778048844 @default.
- W2019397458 hasConcept C2778371730 @default.
- W2019397458 hasConcept C2778675580 @default.
- W2019397458 hasConcept C2779190360 @default.
- W2019397458 hasConcept C2781277250 @default.
- W2019397458 hasConcept C41008148 @default.
- W2019397458 hasConcept C54355233 @default.
- W2019397458 hasConcept C60987743 @default.
- W2019397458 hasConcept C71928629 @default.
- W2019397458 hasConcept C86803240 @default.
- W2019397458 hasConcept C89423630 @default.
- W2019397458 hasConcept C99389464 @default.
- W2019397458 hasConceptScore W2019397458C104317684 @default.
- W2019397458 hasConceptScore W2019397458C136764020 @default.
- W2019397458 hasConceptScore W2019397458C159047783 @default.
- W2019397458 hasConceptScore W2019397458C196843134 @default.
- W2019397458 hasConceptScore W2019397458C203014093 @default.
- W2019397458 hasConceptScore W2019397458C2778048844 @default.
- W2019397458 hasConceptScore W2019397458C2778371730 @default.
- W2019397458 hasConceptScore W2019397458C2778675580 @default.
- W2019397458 hasConceptScore W2019397458C2779190360 @default.
- W2019397458 hasConceptScore W2019397458C2781277250 @default.
- W2019397458 hasConceptScore W2019397458C41008148 @default.
- W2019397458 hasConceptScore W2019397458C54355233 @default.
- W2019397458 hasConceptScore W2019397458C60987743 @default.
- W2019397458 hasConceptScore W2019397458C71928629 @default.
- W2019397458 hasConceptScore W2019397458C86803240 @default.
- W2019397458 hasConceptScore W2019397458C89423630 @default.
- W2019397458 hasConceptScore W2019397458C99389464 @default.
- W2019397458 hasIssue "1" @default.
- W2019397458 hasLocation W20193974581 @default.
- W2019397458 hasLocation W20193974582 @default.
- W2019397458 hasOpenAccess W2019397458 @default.
- W2019397458 hasPrimaryLocation W20193974581 @default.
- W2019397458 hasRelatedWork W2019397458 @default.
- W2019397458 hasRelatedWork W2043610546 @default.
- W2019397458 hasRelatedWork W2057145238 @default.
- W2019397458 hasRelatedWork W2074152516 @default.
- W2019397458 hasRelatedWork W2104550129 @default.
- W2019397458 hasRelatedWork W2150662992 @default.
- W2019397458 hasRelatedWork W2318815378 @default.
- W2019397458 hasRelatedWork W2321041415 @default.
- W2019397458 hasRelatedWork W2562245317 @default.
- W2019397458 hasRelatedWork W279465854 @default.
- W2019397458 hasVolume "43" @default.
- W2019397458 isParatext "false" @default.
- W2019397458 isRetracted "false" @default.
- W2019397458 magId "2019397458" @default.
- W2019397458 workType "article" @default.