FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2019398009> ?p ?o ?g. }

• W2019398009 endingPage "4" @default.
• W2019398009 startingPage "1" @default.
• W2019398009 abstract "Methylenetetrahydrofolate reductase (MTHFR) is an enzyme key regulator in folate metabolism. Deficiencies in MTHFR result in increased levels of homocysteine, which leads to reduced levels of S-adenosylmethionine (SAM). In the brain, SAM donates methyl groups to catechol-O-methyltransferase (COMT), which is involved in neurotransmitter analysis. Using the MTHFR-deficient mouse model the purpose of this study was to investigate levels of monoamine neurotransmitters and amino acid levels in brain tissue. MTHFR deficiency affected levels of both glutamate and γ-aminobutyric acid in within the cerebellum and hippocampus. Mthfr−/− mice had reduced levels of glutamate in the amygdala and γ-aminobutyric acid in the thalamus. The excitatory mechanisms of homocysteine through activation of the N-methyl-d-aspartate receptor in brain tissue might alter levels of glutamate and γ-aminobutyric acid." @default.
• W2019398009 created "2016-06-24" @default.
• W2019398009 creator A5042905167 @default.
• W2019398009 creator A5046050028 @default.
• W2019398009 creator A5062676906 @default.
• W2019398009 creator A5063259918 @default.
• W2019398009 date "2015-06-01" @default.
• W2019398009 modified "2023-10-06" @default.
• W2019398009 title "Methylenetetrahydrofolate reductase deficiency alters levels of glutamate and γ-aminobutyric acid in brain tissue" @default.
• W2019398009 cites W1827005312 @default.
• W2019398009 cites W1984715501 @default.
• W2019398009 cites W1987913873 @default.
• W2019398009 cites W1991906615 @default.
• W2019398009 cites W2008770673 @default.
• W2019398009 cites W2012022071 @default.
• W2019398009 cites W2021088194 @default.
• W2019398009 cites W2024225004 @default.
• W2019398009 cites W2028458982 @default.
• W2019398009 cites W2066688265 @default.
• W2019398009 cites W2067153292 @default.
• W2019398009 cites W2074201510 @default.
• W2019398009 cites W2077949190 @default.
• W2019398009 cites W2084692086 @default.
• W2019398009 cites W2090639347 @default.
• W2019398009 cites W2093142078 @default.
• W2019398009 cites W2117889142 @default.
• W2019398009 cites W2134408917 @default.
• W2019398009 cites W2139481908 @default.
• W2019398009 cites W2140483277 @default.
• W2019398009 cites W2152482512 @default.
• W2019398009 cites W2153606794 @default.
• W2019398009 cites W2155384243 @default.
• W2019398009 cites W2159235381 @default.
• W2019398009 cites W2165715420 @default.
• W2019398009 cites W2404543162 @default.
• W2019398009 cites W4244589373 @default.
• W2019398009 cites W4299540435 @default.
• W2019398009 cites W4376550259 @default.
• W2019398009 doi "https://doi.org/10.1016/j.ymgmr.2015.02.001" @default.
• W2019398009 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4750636" @default.
• W2019398009 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26937386" @default.
• W2019398009 hasPublicationYear "2015" @default.
• W2019398009 type Work @default.
• W2019398009 sameAs 2019398009 @default.
• W2019398009 citedByCount "21" @default.
• W2019398009 countsByYear W20193980092016 @default.
• W2019398009 countsByYear W20193980092017 @default.
• W2019398009 countsByYear W20193980092018 @default.
• W2019398009 countsByYear W20193980092019 @default.
• W2019398009 countsByYear W20193980092020 @default.
• W2019398009 countsByYear W20193980092021 @default.
• W2019398009 countsByYear W20193980092022 @default.
• W2019398009 countsByYear W20193980092023 @default.
• W2019398009 crossrefType "journal-article" @default.
• W2019398009 hasAuthorship W2019398009A5042905167 @default.
• W2019398009 hasAuthorship W2019398009A5046050028 @default.
• W2019398009 hasAuthorship W2019398009A5062676906 @default.
• W2019398009 hasAuthorship W2019398009A5063259918 @default.
• W2019398009 hasBestOaLocation W20193980091 @default.
• W2019398009 hasConcept C104317684 @default.
• W2019398009 hasConcept C126322002 @default.
• W2019398009 hasConcept C134018914 @default.
• W2019398009 hasConcept C135763542 @default.
• W2019398009 hasConcept C170493617 @default.
• W2019398009 hasConcept C185592680 @default.
• W2019398009 hasConcept C2776219046 @default.
• W2019398009 hasConcept C2777090595 @default.
• W2019398009 hasConcept C43563269 @default.
• W2019398009 hasConcept C55493867 @default.
• W2019398009 hasConcept C61174792 @default.
• W2019398009 hasConcept C71924100 @default.
• W2019398009 hasConcept C86803240 @default.
• W2019398009 hasConceptScore W2019398009C104317684 @default.
• W2019398009 hasConceptScore W2019398009C126322002 @default.
• W2019398009 hasConceptScore W2019398009C134018914 @default.
• W2019398009 hasConceptScore W2019398009C135763542 @default.
• W2019398009 hasConceptScore W2019398009C170493617 @default.
• W2019398009 hasConceptScore W2019398009C185592680 @default.
• W2019398009 hasConceptScore W2019398009C2776219046 @default.
• W2019398009 hasConceptScore W2019398009C2777090595 @default.
• W2019398009 hasConceptScore W2019398009C43563269 @default.
• W2019398009 hasConceptScore W2019398009C55493867 @default.
• W2019398009 hasConceptScore W2019398009C61174792 @default.
• W2019398009 hasConceptScore W2019398009C71924100 @default.
• W2019398009 hasConceptScore W2019398009C86803240 @default.
• W2019398009 hasFunder F4320320879 @default.
• W2019398009 hasLocation W20193980091 @default.
• W2019398009 hasLocation W20193980092 @default.
• W2019398009 hasLocation W20193980093 @default.
• W2019398009 hasLocation W20193980094 @default.
• W2019398009 hasLocation W20193980095 @default.
• W2019398009 hasOpenAccess W2019398009 @default.
• W2019398009 hasPrimaryLocation W20193980091 @default.
• W2019398009 hasRelatedWork W1966504330 @default.
• W2019398009 hasRelatedWork W1979139803 @default.
• W2019398009 hasRelatedWork W2018392946 @default.
• W2019398009 hasRelatedWork W2027622212 @default.
• W2019398009 hasRelatedWork W2037631372 @default.

• next