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- W2019414003 abstract "Different RIA systems available for measuring the concentrations of pregnancy-associated glycoproteins (PAGs) in dairy goats were compared in order to evaluate their accuracy in early pregnancy diagnosis. Plasma concentrations of PAGs were determined by 3 heterologous RIA systems with a bovine PAG standard and tracer in combination with antisera anti-ovine PAG (RIA 1), anti-caprine PAG55+62 (RIA 2), anti-caprine PAG55+59 (RIA 3), and by 2 homologous RIA systems that employed caprine PAG55+62 and caprine PAG55+59 and their specific antisera (RIAs 4 and 5, respectively). In all of the RIAs, the mean concentrations of PAGs were significantly higher (P < 0.01) in pregnant than in nonpregnant goats from Day 21 onwards after breeding. On Day 21, the accuracy rates of early pregnancy diagnoses were 56% (RIA 1), 96% (RIA 2), 99% (RIA 3), 95% (RIA 4) and 90% (RIA 5), whereas on Day 28 these rates were >99% for RIAs 2, 3, 4 and 5. The RIAs for PAGs depend on proteins from the placenta being present in maternal plasma and require only a single sample of blood, to distinguish pregnant goats from those that fail to return to estrus for other reasons. The homologous and semiheterologous assays are highly accurate as early as Day 21 of pregnancy." @default.
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- W2019414003 date "1999-09-01" @default.
- W2019414003 modified "2023-10-18" @default.
- W2019414003 title "Early pregnancy diagnosis in goats by determination of pregnancy-associated glycoprotein concentrations in plasma samples" @default.
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- W2019414003 doi "https://doi.org/10.1016/s0093-691x(99)00165-x" @default.
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