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- W2019414198 abstract "Characteristics of left atrial receptors were studied in normotensive control (Wistar) and spontaneously hypertensive rats. The left atrial pressure was chronically elevated in spontaneously hypertensive rats and at the end of the expiratory phase was 10.3 mm Hg as compared with 4.6 mm Hg in normotensive control rats. The thresholds of the receptor endings were twice as high in the hypertensive as in the normotensive rats (10.2 and 4.6 mm Hg, respectively). In other experiments the reflex inhibition of renal sympathetic outflow was studied during plasma infusion in baroreceptor denervated normotensive and hypertensive rats and was inhibited at a lower left atrial pressure in the former. These differences are attributed to decreased distensibility of the left atrium in spontaneously hypertensive rats. The reflex splanchnic nerve inhibition with volume load also was recorded in awake rats. At a 10 percent increase in blood volume, splanchnic outflow was more significantly decreased in spontaneously hypertensive than in normotensive rats. The mechanism underlying such a hyperreactive volume receptor response is unknown, but a less distensible venous system, centrally or peripherally, might be a contributing factor." @default.
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- W2019414198 title "Cardiac reflexes in normotensive and spontaneously hypertensive rats" @default.
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- W2019414198 doi "https://doi.org/10.1016/0002-9149(79)90218-2" @default.
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