Matches in SemOpenAlex for { <https://semopenalex.org/work/W2019425575> ?p ?o ?g. }
Showing items 1 to 99 of
99
with 100 items per page.
- W2019425575 endingPage "361" @default.
- W2019425575 startingPage "353" @default.
- W2019425575 abstract "An in vitro superfusion system was used in an attempt to identify the cellular systems involved in the Ca2+ dependence of gonadotropin-releasing hormone (GnRH) actions in the frog, Rana pipiens. Superfusion with 5 microM A23187 (a calcium ionophore) or phorbol myristate acetate (an analog of diacylglycerides) caused marked increases in luteinizing hormone (LH) and follicle-stimulating hormone (FSH) secretion. Exclusion of Ca2+ from the medium prevented the stimulatory effects of PMA. The potent stimulator of adenylate cyclase, forskolin, caused only slight stimulation of LH and FSH secretion, which was also prevented by removal of Ca2+. The cytoskeletal disruptive agents colchicine, nocodazole, and cytochalasin B, and the calmodulin inhibitors, trifluoperazine and pimozide, had no significant effects on the action of GnRH. Overall, these results indicate that the major mechanisms of Ca2+ involvement in the response to GnRH by the frog pituitary are similar to that of mammals, with the possible exceptions of lesser roles for calmodulin and the cytoskeleton in the frog. The study suggests that polyphosphatidyl-inositol-diacylglyceride metabolism may be critical in understanding the mechanism of GnRH action in frogs." @default.
- W2019425575 created "2016-06-24" @default.
- W2019425575 creator A5029360964 @default.
- W2019425575 creator A5030618575 @default.
- W2019425575 date "1986-12-01" @default.
- W2019425575 modified "2023-09-27" @default.
- W2019425575 title "The cellular basis of the calcium dependence of GnRH-stimulated gonadotropin release from frog,Rana pipiens, pituitaries" @default.
- W2019425575 cites W1973192753 @default.
- W2019425575 cites W1974422639 @default.
- W2019425575 cites W1978151819 @default.
- W2019425575 cites W1983005890 @default.
- W2019425575 cites W1989809535 @default.
- W2019425575 cites W1994924034 @default.
- W2019425575 cites W1996975556 @default.
- W2019425575 cites W2001692359 @default.
- W2019425575 cites W2007857033 @default.
- W2019425575 cites W2009291798 @default.
- W2019425575 cites W2011060678 @default.
- W2019425575 cites W2012631132 @default.
- W2019425575 cites W2019402896 @default.
- W2019425575 cites W2019574692 @default.
- W2019425575 cites W2024657845 @default.
- W2019425575 cites W2027704731 @default.
- W2019425575 cites W2029169169 @default.
- W2019425575 cites W2029500865 @default.
- W2019425575 cites W2034037477 @default.
- W2019425575 cites W2048122210 @default.
- W2019425575 cites W2052349713 @default.
- W2019425575 cites W2053697042 @default.
- W2019425575 cites W2060642257 @default.
- W2019425575 cites W2062535763 @default.
- W2019425575 cites W2070211997 @default.
- W2019425575 cites W2070999156 @default.
- W2019425575 cites W2078550902 @default.
- W2019425575 cites W2082670517 @default.
- W2019425575 cites W2130154023 @default.
- W2019425575 cites W2166721020 @default.
- W2019425575 doi "https://doi.org/10.1002/jez.1402400309" @default.
- W2019425575 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3098896" @default.
- W2019425575 hasPublicationYear "1986" @default.
- W2019425575 type Work @default.
- W2019425575 sameAs 2019425575 @default.
- W2019425575 citedByCount "4" @default.
- W2019425575 countsByYear W20194255752018 @default.
- W2019425575 crossrefType "journal-article" @default.
- W2019425575 hasAuthorship W2019425575A5029360964 @default.
- W2019425575 hasAuthorship W2019425575A5030618575 @default.
- W2019425575 hasConcept C126322002 @default.
- W2019425575 hasConcept C134018914 @default.
- W2019425575 hasConcept C202751555 @default.
- W2019425575 hasConcept C24998067 @default.
- W2019425575 hasConcept C2778575703 @default.
- W2019425575 hasConcept C2778894405 @default.
- W2019425575 hasConcept C2779012151 @default.
- W2019425575 hasConcept C2779276759 @default.
- W2019425575 hasConcept C2781130464 @default.
- W2019425575 hasConcept C29688787 @default.
- W2019425575 hasConcept C519063684 @default.
- W2019425575 hasConcept C55493867 @default.
- W2019425575 hasConcept C71315377 @default.
- W2019425575 hasConcept C71924100 @default.
- W2019425575 hasConcept C86803240 @default.
- W2019425575 hasConceptScore W2019425575C126322002 @default.
- W2019425575 hasConceptScore W2019425575C134018914 @default.
- W2019425575 hasConceptScore W2019425575C202751555 @default.
- W2019425575 hasConceptScore W2019425575C24998067 @default.
- W2019425575 hasConceptScore W2019425575C2778575703 @default.
- W2019425575 hasConceptScore W2019425575C2778894405 @default.
- W2019425575 hasConceptScore W2019425575C2779012151 @default.
- W2019425575 hasConceptScore W2019425575C2779276759 @default.
- W2019425575 hasConceptScore W2019425575C2781130464 @default.
- W2019425575 hasConceptScore W2019425575C29688787 @default.
- W2019425575 hasConceptScore W2019425575C519063684 @default.
- W2019425575 hasConceptScore W2019425575C55493867 @default.
- W2019425575 hasConceptScore W2019425575C71315377 @default.
- W2019425575 hasConceptScore W2019425575C71924100 @default.
- W2019425575 hasConceptScore W2019425575C86803240 @default.
- W2019425575 hasIssue "3" @default.
- W2019425575 hasLocation W20194255751 @default.
- W2019425575 hasLocation W20194255752 @default.
- W2019425575 hasOpenAccess W2019425575 @default.
- W2019425575 hasPrimaryLocation W20194255751 @default.
- W2019425575 hasRelatedWork W1926655306 @default.
- W2019425575 hasRelatedWork W1966445265 @default.
- W2019425575 hasRelatedWork W1970061594 @default.
- W2019425575 hasRelatedWork W1981222718 @default.
- W2019425575 hasRelatedWork W2025304600 @default.
- W2019425575 hasRelatedWork W2067589401 @default.
- W2019425575 hasRelatedWork W2070386770 @default.
- W2019425575 hasRelatedWork W2164933659 @default.
- W2019425575 hasRelatedWork W4238226706 @default.
- W2019425575 hasRelatedWork W4252329896 @default.
- W2019425575 hasVolume "240" @default.
- W2019425575 isParatext "false" @default.
- W2019425575 isRetracted "false" @default.
- W2019425575 magId "2019425575" @default.
- W2019425575 workType "article" @default.