FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2019425757> ?p ?o ?g. }

• W2019425757 abstract "Relapse triggered by drug-paired cues is a major obstacle for successful treatment of drug abuse. Patterns of brain activation induced by drug-paired cues have been identified in human and animal models, but lack of specificity poses a serious problem for craving or relapse interpretations. The goal of this study was to compare brain responses to contextual cues paired with a rewarding versus an aversive stimulus in a mouse model to test the hypothesis that different patterns of brain activation can be detected. Mice were trained to associate a common environmental context with an intraperitoneal injection of saline, lithium chloride or cocaine. After measuring each animal for conditioned place preference or aversion, mice were re-exposed to the context (CS+ or CS-) in absence of the reinforcer to analyze patterns of Fos expression in 10 brain regions chosen from previous literature. Levels of Fos in the cingulate cortex, paraventricular thalamic nucleus, paraventricular hypothalamic nucleus, and dentate gyrus differed in CS+ versus CS- groups, but the direction of the differences was the same for both lithium chloride (LiCl) and cocaine reinforcers. In the cingulate cortex, Fos was positively correlated with degree of place preference for cocaine or aversion to LiCl whereas in the periaqueductal gray the relationship was positive for LiCl and negative for cocaine. Results confirm Fos responses to reward- or aversion-paired cues are similar but specificity is detectable. Future studies are needed to comprehensively establish neuroanatomical specificity in conditioned responses to drugs as compared to other reinforcers." @default.
• W2019425757 created "2016-06-24" @default.
• W2019425757 creator A5049958260 @default.
• W2019425757 creator A5053942773 @default.
• W2019425757 creator A5056938624 @default.
• W2019425757 creator A5068937742 @default.
• W2019425757 date "2010-03-01" @default.
• W2019425757 modified "2023-09-26" @default.
• W2019425757 title "A similar pattern of neuronal Fos activation in 10 brain regions following exposure to reward- or aversion-associated contextual cues in mice" @default.
• W2019425757 cites W1605427252 @default.
• W2019425757 cites W1614699707 @default.
• W2019425757 cites W1680771593 @default.
• W2019425757 cites W1969528791 @default.
• W2019425757 cites W1975190631 @default.
• W2019425757 cites W1976999450 @default.
• W2019425757 cites W1980119771 @default.
• W2019425757 cites W1984101306 @default.
• W2019425757 cites W1984336157 @default.
• W2019425757 cites W1990582382 @default.
• W2019425757 cites W1992028615 @default.
• W2019425757 cites W1995954315 @default.
• W2019425757 cites W2000696407 @default.
• W2019425757 cites W2002482831 @default.
• W2019425757 cites W2016653090 @default.
• W2019425757 cites W2027655628 @default.
• W2019425757 cites W2038566061 @default.
• W2019425757 cites W2041515812 @default.
• W2019425757 cites W2044927010 @default.
• W2019425757 cites W2046126247 @default.
• W2019425757 cites W2052004347 @default.
• W2019425757 cites W2060189035 @default.
• W2019425757 cites W2063055166 @default.
• W2019425757 cites W2064879747 @default.
• W2019425757 cites W2070426314 @default.
• W2019425757 cites W2072009783 @default.
• W2019425757 cites W2079322728 @default.
• W2019425757 cites W2080046881 @default.
• W2019425757 cites W2084442578 @default.
• W2019425757 cites W2092115109 @default.
• W2019425757 cites W2093354584 @default.
• W2019425757 cites W2098304576 @default.
• W2019425757 cites W2101995552 @default.
• W2019425757 cites W2103263170 @default.
• W2019425757 cites W2105381419 @default.
• W2019425757 cites W2109078253 @default.
• W2019425757 cites W2120411894 @default.
• W2019425757 cites W2121622204 @default.
• W2019425757 cites W2122591357 @default.
• W2019425757 cites W2125635982 @default.
• W2019425757 cites W2126502833 @default.
• W2019425757 cites W2129688965 @default.
• W2019425757 cites W2148655327 @default.
• W2019425757 cites W2155154508 @default.
• W2019425757 cites W2158069518 @default.
• W2019425757 cites W2170276695 @default.
• W2019425757 doi "https://doi.org/10.1016/j.physbeh.2009.12.013" @default.
• W2019425757 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2813902" @default.
• W2019425757 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20026143" @default.
• W2019425757 hasPublicationYear "2010" @default.
• W2019425757 type Work @default.
• W2019425757 sameAs 2019425757 @default.
• W2019425757 citedByCount "23" @default.
• W2019425757 countsByYear W20194257572012 @default.
• W2019425757 countsByYear W20194257572013 @default.
• W2019425757 countsByYear W20194257572014 @default.
• W2019425757 countsByYear W20194257572015 @default.
• W2019425757 countsByYear W20194257572016 @default.
• W2019425757 countsByYear W20194257572017 @default.
• W2019425757 countsByYear W20194257572018 @default.
• W2019425757 countsByYear W20194257572022 @default.
• W2019425757 crossrefType "journal-article" @default.
• W2019425757 hasAuthorship W2019425757A5049958260 @default.
• W2019425757 hasAuthorship W2019425757A5053942773 @default.
• W2019425757 hasAuthorship W2019425757A5056938624 @default.
• W2019425757 hasAuthorship W2019425757A5068937742 @default.
• W2019425757 hasBestOaLocation W20194257572 @default.
• W2019425757 hasConcept C151730666 @default.
• W2019425757 hasConcept C15744967 @default.
• W2019425757 hasConcept C169760540 @default.
• W2019425757 hasConcept C180747234 @default.
• W2019425757 hasConcept C2779144063 @default.
• W2019425757 hasConcept C2779343474 @default.
• W2019425757 hasConcept C2779541405 @default.
• W2019425757 hasConcept C2779918689 @default.
• W2019425757 hasConcept C2781210436 @default.
• W2019425757 hasConcept C35124327 @default.
• W2019425757 hasConcept C48856860 @default.
• W2019425757 hasConcept C529278444 @default.
• W2019425757 hasConcept C86803240 @default.
• W2019425757 hasConceptScore W2019425757C151730666 @default.
• W2019425757 hasConceptScore W2019425757C15744967 @default.
• W2019425757 hasConceptScore W2019425757C169760540 @default.
• W2019425757 hasConceptScore W2019425757C180747234 @default.
• W2019425757 hasConceptScore W2019425757C2779144063 @default.
• W2019425757 hasConceptScore W2019425757C2779343474 @default.
• W2019425757 hasConceptScore W2019425757C2779541405 @default.
• W2019425757 hasConceptScore W2019425757C2779918689 @default.
• W2019425757 hasConceptScore W2019425757C2781210436 @default.
• W2019425757 hasConceptScore W2019425757C35124327 @default.
• W2019425757 hasConceptScore W2019425757C48856860 @default.

• next