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• W2019427044 endingPage "1971" @default.
• W2019427044 startingPage "1961" @default.
• W2019427044 abstract "A database of nonredundant structures of EF-hand domainsi.e., pairs of helix-loop-helix motifshas been assembled, and the six angles among the four helices re-determined. A principal component analysis of these angles allows us to use two such components (PC1 and PC2) to describe the system retaining 80% of the total variance. A PC2 against PC1 plot representation allows us to represent in a compact way the full range of structural diversity of EF-hand domains, their grouping into protein families, and the variation for each family upon calcium and peptide binding. Keywords: EF-hand • principal component analysis • calcium binding • interhelical angle • structural analysis" @default.
• W2019427044 created "2016-06-24" @default.
• W2019427044 creator A5016319366 @default.
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• W2019427044 date "2005-11-05" @default.
• W2019427044 modified "2023-10-17" @default.
• W2019427044 title "Principal Component Analysis of the Conformational Freedom within the EF-Hand Superfamily" @default.
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• W2019427044 doi "https://doi.org/10.1021/pr050148n" @default.
• W2019427044 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16335940" @default.
• W2019427044 hasPublicationYear "2005" @default.
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