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- W2019434845 abstract "The type 2 ribosome-inactivating proteins (RIPs) isolated from some species belonging to the Sambucus genus, have the characteristic that although being even more active than ricin inhibiting protein synthesis in cell-free extracts, they lack the high toxicity of ricin and related type 2 RIPs to intact cells and animals. This is due to the fact that after internalization, they follow a different intracellular pathway that does not allow them to reach the cytosolic ribosomes. The lack of toxicity of type 2 RIPs from Sambucus make them good candidates as toxic moieties in the construction of immunotoxins and conjugates directed against specific targets. Up to now they have been conjugated with either transferrin or anti-CD105 to target either transferrin receptor- or endoglin-overexpressing cells, respectively." @default.
- W2019434845 created "2016-06-24" @default.
- W2019434845 creator A5023487943 @default.
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- W2019434845 creator A5060662876 @default.
- W2019434845 creator A5071801703 @default.
- W2019434845 creator A5074002716 @default.
- W2019434845 date "2011-04-29" @default.
- W2019434845 modified "2023-10-01" @default.
- W2019434845 title "Use of Ribosome-Inactivating Proteins from Sambucus for the Construction of Immunotoxins and Conjugates for Cancer Therapy" @default.
- W2019434845 cites W122132233 @default.
- W2019434845 cites W128869094 @default.
- W2019434845 cites W1514205868 @default.
- W2019434845 cites W1531093913 @default.
- W2019434845 cites W1545864101 @default.
- W2019434845 cites W1552152044 @default.
- W2019434845 cites W1563956190 @default.
- W2019434845 cites W1567197932 @default.
- W2019434845 cites W1593572360 @default.
- W2019434845 cites W1963872061 @default.
- W2019434845 cites W1964812214 @default.
- W2019434845 cites W1965184509 @default.
- W2019434845 cites W1965226579 @default.
- W2019434845 cites W1978352485 @default.
- W2019434845 cites W1978576726 @default.
- W2019434845 cites W1982626189 @default.
- W2019434845 cites W1985119607 @default.
- W2019434845 cites W1985456114 @default.
- W2019434845 cites W1985485047 @default.
- W2019434845 cites W1985542042 @default.
- W2019434845 cites W1985804036 @default.
- W2019434845 cites W1989943717 @default.
- W2019434845 cites W1990810351 @default.
- W2019434845 cites W1991205701 @default.
- W2019434845 cites W1993546257 @default.
- W2019434845 cites W2000000541 @default.
- W2019434845 cites W2002414413 @default.
- W2019434845 cites W2003022058 @default.
- W2019434845 cites W2003338204 @default.
- W2019434845 cites W2003937464 @default.
- W2019434845 cites W2004738840 @default.
- W2019434845 cites W2005241199 @default.
- W2019434845 cites W2005753131 @default.
- W2019434845 cites W2009609107 @default.
- W2019434845 cites W2010900024 @default.
- W2019434845 cites W2012796753 @default.
- W2019434845 cites W2017288623 @default.
- W2019434845 cites W2018362093 @default.
- W2019434845 cites W2021288306 @default.
- W2019434845 cites W2021374145 @default.
- W2019434845 cites W2022143560 @default.
- W2019434845 cites W2023949193 @default.
- W2019434845 cites W2028156849 @default.
- W2019434845 cites W2030692792 @default.
- W2019434845 cites W2031157920 @default.
- W2019434845 cites W2033545943 @default.
- W2019434845 cites W2036602174 @default.
- W2019434845 cites W2039583599 @default.
- W2019434845 cites W2040605843 @default.
- W2019434845 cites W2041649032 @default.
- W2019434845 cites W2043922049 @default.
- W2019434845 cites W2043967922 @default.
- W2019434845 cites W2045564059 @default.
- W2019434845 cites W2046801869 @default.
- W2019434845 cites W2047089640 @default.
- W2019434845 cites W2053302835 @default.
- W2019434845 cites W2053656795 @default.
- W2019434845 cites W2053748618 @default.
- W2019434845 cites W2053794928 @default.
- W2019434845 cites W2055133784 @default.
- W2019434845 cites W2058183392 @default.
- W2019434845 cites W2062348697 @default.
- W2019434845 cites W2063689911 @default.
- W2019434845 cites W2065022006 @default.
- W2019434845 cites W2065947474 @default.
- W2019434845 cites W2068026334 @default.
- W2019434845 cites W2068507373 @default.
- W2019434845 cites W2070145126 @default.
- W2019434845 cites W2070880734 @default.
- W2019434845 cites W2076863296 @default.
- W2019434845 cites W2079923013 @default.
- W2019434845 cites W2084579153 @default.
- W2019434845 cites W2084867908 @default.
- W2019434845 cites W2085523190 @default.
- W2019434845 cites W2086604931 @default.
- W2019434845 cites W2087569351 @default.
- W2019434845 cites W2091945624 @default.
- W2019434845 cites W2093003732 @default.
- W2019434845 cites W2099561080 @default.
- W2019434845 cites W2100446922 @default.
- W2019434845 cites W2101239339 @default.
- W2019434845 cites W2106443011 @default.
- W2019434845 cites W2115393735 @default.
- W2019434845 cites W2122527623 @default.
- W2019434845 cites W2126794583 @default.
- W2019434845 cites W2134603606 @default.
- W2019434845 cites W2136593707 @default.
- W2019434845 cites W2137596847 @default.