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- W2019436240 abstract "A reversed phase HPLC method for the determination of carbamazepine (CBZ) in the brain of adult mice is described. CBZ was recovered from murine brain by solvent-extraction with ethyl acetate and resolved from imipramine (internal standard) and brain endogenous material using a Lichrospher RP select B column with a linear gradient of acetonitrile (40-80 v/v, 25 min) in ammonium acetate buffer (25 mM, pH 4.0) with UV detection at 285 nm. The method is selective, reproducible and precise with a limit detection of 45 ng/ml and is suitable for the determination of CBZ in murine brain after intra-peritoneal administration." @default.
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- W2019436240 date "2001-11-01" @default.
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- W2019436240 title "LC determination of carbamazepine in murine brain" @default.
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- W2019436240 doi "https://doi.org/10.1016/s0731-7085(01)00477-0" @default.
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