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- W2019436727 abstract "IL12R defekti mendelian mikobakteriyel yatkinlik hastaligi (MMYH)’nin en sik gorulen sebebidir. BCG enfeksiyonu ile ilk bulgularini verebilir. BCG asisi yerinde gecmeyen yara, eklem sislikleri, hepatosplenomegali ve notropeni sebebi ile yillarca genel pediatri polikliniginde izlenen 9 yasinda erkek hasta sunuldu. Hasta lenfositleri in vitro IL12 uyarisina IFNg cevabi vermedigi icin, bu hastanin IL12R defekti oldugu dusunuldu. BCG asisi yerinde enfeksiyon gelisen hastalar MMYH acisindan degerlendirilmelidir.A child diagnosed as IL12R defect with disseminated BCG infectionBackground: IL12R defect is the most common genetic etiology of Mendelian susceptibility to mycobacterial disease (MSMD). It can be firstly diagnosed as BCGitis.Case: Nine year old boy admitted with ulcerative lesion on second BCG vaccine site. He sometimes experienced arthritis, hepatosplenomegaly and neutropenia. The lymphocytes of the child has no response to IFNg in vitro, the patient diagnose as IL12R defect. Conclusion: The patients who have BCGitis should be evaluated for MSMD." @default.
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- W2019436727 date "2011-02-08" @default.
- W2019436727 modified "2023-10-17" @default.
- W2019436727 title "Yaygın BCG Enfeksiyonu Olan IL12R Defekti Olgusu" @default.
- W2019436727 doi "https://doi.org/10.5835/jecm.v27i2.112" @default.
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