FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2019443835> ?p ?o ?g. }

• W2019443835 endingPage "1663" @default.
• W2019443835 startingPage "1655" @default.
• W2019443835 abstract "Reactive immunoblastic proliferations can histologically mimic classical Hodgkin lymphoma (CHL), and show diffuse CD30 expression in large cells. The lack of expression of CD15 in a subset of CHL further complicates their separation from immunoblastic proliferations. Loss of expression of B-cell transcription factors is frequently exploited in making a diagnosis of CHL; however, the staining patterns of B-cell transcription factors in immunoblastic proliferations have not been extensively studied. Thirty-three cases of reactive immunoblastic proliferations were evaluated using a panel of immunohistochemistry for CD30, CD15, CD20, CD3, κ, λ, CD45RB, MUM1, PAX5, OCT2, and BOB.1, as well as Epstein-Barr virus (EBV)/EBV-encoded ribonucleic acid in situ hybridization. A newly developed dual-color chromogenic in situ hybridization technology for detection of κ/λ mRNAs was also used. The majority of immunoblasts expressed CD30 in 14 of 33 (42%) cases; none expressed CD15. Loss or weak expression of at least 1 transcription factor in B immunoblasts, most commonly PAX5, was noted in 24 of 29 (83%) cases. A polytypic light chain expression pattern was detected by immunohistochemistry in 14 of 22 (63.6%) cases and by dual-color chromogenic in situ hybridization in 9 of 10 (90%) cases studied. EBV-encoded ribonucleic acid was detected in 8 of 33 (24.2%) cases, 5 of which were clinically unrelated to infectious mononucleosis. We conclude that B-cell transcription factors can show loss or weak expression in a significant proportion of reactive immunoblastic proliferations, and, therefore, staining for B-cell transcription factors together with CD30 should be interpreted with caution before a diagnosis of CHL is made." @default.
• W2019443835 created "2016-06-24" @default.
• W2019443835 creator A5001976357 @default.
• W2019443835 creator A5005010207 @default.
• W2019443835 creator A5012160968 @default.
• W2019443835 creator A5071127912 @default.
• W2019443835 creator A5080313708 @default.
• W2019443835 date "2014-12-01" @default.
• W2019443835 modified "2023-09-30" @default.
• W2019443835 title "Variable Expression of B-cell Transcription Factors in Reactive Immunoblastic Proliferations" @default.
• W2019443835 cites W1649547160 @default.
• W2019443835 cites W1964478384 @default.
• W2019443835 cites W1972108415 @default.
• W2019443835 cites W1976892770 @default.
• W2019443835 cites W1992406304 @default.
• W2019443835 cites W1994845245 @default.
• W2019443835 cites W2010362735 @default.
• W2019443835 cites W2021295339 @default.
• W2019443835 cites W2027504053 @default.
• W2019443835 cites W2035995168 @default.
• W2019443835 cites W2038612213 @default.
• W2019443835 cites W2043976161 @default.
• W2019443835 cites W2048026755 @default.
• W2019443835 cites W2049143215 @default.
• W2019443835 cites W2049629827 @default.
• W2019443835 cites W2055907134 @default.
• W2019443835 cites W2056287698 @default.
• W2019443835 cites W2057712020 @default.
• W2019443835 cites W2059280119 @default.
• W2019443835 cites W2063974591 @default.
• W2019443835 cites W2066416336 @default.
• W2019443835 cites W2072652227 @default.
• W2019443835 cites W2073154035 @default.
• W2019443835 cites W2077013919 @default.
• W2019443835 cites W2078771853 @default.
• W2019443835 cites W2132753386 @default.
• W2019443835 cites W2136978079 @default.
• W2019443835 cites W2153464648 @default.
• W2019443835 cites W2328139329 @default.
• W2019443835 cites W2398456118 @default.
• W2019443835 cites W4244605157 @default.
• W2019443835 cites W96192748 @default.
• W2019443835 doi "https://doi.org/10.1097/pas.0000000000000266" @default.
• W2019443835 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24921642" @default.
• W2019443835 hasPublicationYear "2014" @default.
• W2019443835 type Work @default.
• W2019443835 sameAs 2019443835 @default.
• W2019443835 citedByCount "12" @default.
• W2019443835 countsByYear W20194438352014 @default.
• W2019443835 countsByYear W20194438352016 @default.
• W2019443835 countsByYear W20194438352018 @default.
• W2019443835 countsByYear W20194438352019 @default.
• W2019443835 countsByYear W20194438352020 @default.
• W2019443835 countsByYear W20194438352021 @default.
• W2019443835 countsByYear W20194438352022 @default.
• W2019443835 countsByYear W20194438352023 @default.
• W2019443835 crossrefType "journal-article" @default.
• W2019443835 hasAuthorship W2019443835A5001976357 @default.
• W2019443835 hasAuthorship W2019443835A5005010207 @default.
• W2019443835 hasAuthorship W2019443835A5012160968 @default.
• W2019443835 hasAuthorship W2019443835A5071127912 @default.
• W2019443835 hasAuthorship W2019443835A5080313708 @default.
• W2019443835 hasConcept C10205521 @default.
• W2019443835 hasConcept C104317684 @default.
• W2019443835 hasConcept C142724271 @default.
• W2019443835 hasConcept C150194340 @default.
• W2019443835 hasConcept C153911025 @default.
• W2019443835 hasConcept C18031839 @default.
• W2019443835 hasConcept C204232928 @default.
• W2019443835 hasConcept C2776643354 @default.
• W2019443835 hasConcept C2776804306 @default.
• W2019443835 hasConcept C28328180 @default.
• W2019443835 hasConcept C29447677 @default.
• W2019443835 hasConcept C54355233 @default.
• W2019443835 hasConcept C70905583 @default.
• W2019443835 hasConcept C71924100 @default.
• W2019443835 hasConcept C81439078 @default.
• W2019443835 hasConcept C86339819 @default.
• W2019443835 hasConcept C86803240 @default.
• W2019443835 hasConceptScore W2019443835C10205521 @default.
• W2019443835 hasConceptScore W2019443835C104317684 @default.
• W2019443835 hasConceptScore W2019443835C142724271 @default.
• W2019443835 hasConceptScore W2019443835C150194340 @default.
• W2019443835 hasConceptScore W2019443835C153911025 @default.
• W2019443835 hasConceptScore W2019443835C18031839 @default.
• W2019443835 hasConceptScore W2019443835C204232928 @default.
• W2019443835 hasConceptScore W2019443835C2776643354 @default.
• W2019443835 hasConceptScore W2019443835C2776804306 @default.
• W2019443835 hasConceptScore W2019443835C28328180 @default.
• W2019443835 hasConceptScore W2019443835C29447677 @default.
• W2019443835 hasConceptScore W2019443835C54355233 @default.
• W2019443835 hasConceptScore W2019443835C70905583 @default.
• W2019443835 hasConceptScore W2019443835C71924100 @default.
• W2019443835 hasConceptScore W2019443835C81439078 @default.
• W2019443835 hasConceptScore W2019443835C86339819 @default.
• W2019443835 hasConceptScore W2019443835C86803240 @default.
• W2019443835 hasIssue "12" @default.
• W2019443835 hasLocation W20194438351 @default.

• next