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• W2019455732 abstract "A new general method for the preparation of 2-alkyl-pipecolic acids has been developed. The syntheses of 2-methyl-, 2-benzyl- and cis-6-methylpipecolic acids are described. (−)S- and (+)R-2-methylpipecolic acids were resolved by fractional crystallization of the quinine salt of their N-carbobenzoxy derivative. Isolation of (−)S-cis-6-methylpipecolic acid required the use of 4-phenylbenzyloxycarbonyl as protecting group to achieve selective crystallization of the quinine salt. The absolute configurations of these compounds were determined by circular dichroism." @default.
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• W2019455732 date "1983-01-01" @default.
• W2019455732 modified "2023-10-16" @default.
• W2019455732 title "Synthesis and resolution of substituted pipecolic acids" @default.
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• W2019455732 doi "https://doi.org/10.1016/0014-3057(83)90072-1" @default.
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