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- W2019466835 abstract "To compare 2 different application methods of mitomycin C (MMC) in patients undergoing trabeculectomy. This retrospective trial compared outcomes of 191 eyes that underwent trabeculectomy with small-area (96 eyes; 50.3%) and large-area (95 eyes; 49.7%) MMC application. Main outcome measures were changes in intraocular pressure (IOP), required glaucoma medications, the frequency of complications, and postsurgical interventions. Within both treatment groups, a highly significant IOP reduction was seen during follow-up (p < 0.0001). Statistical analyses revealed a significant difference in IOP between both groups. Patients treated with a larger size of surface area had a higher IOP reduction within the first postoperative year. Choroidal detachment, shallow anterior chamber, and bleb leak were seen more often in the large-area group with more aggressive MMC use. In contrast, complications associated with bleb failure such as bleb scarring were higher in the small-area group. Success rate was higher in the large-area MMC application group after 12 months. Large-area treatment seems to be a more efficient application method of MMC during trabeculectomy." @default.
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- W2019466835 date "2013-09-01" @default.
- W2019466835 modified "2023-09-27" @default.
- W2019466835 title "Large-area versus Small-area Application of Mitomycin C during Trabeculectomy" @default.
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- W2019466835 doi "https://doi.org/10.5301/ejo.5000287" @default.
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