FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2019467771> ?p ?o ?g. }

• W2019467771 endingPage "R36" @default.
• W2019467771 startingPage "R36" @default.
• W2019467771 abstract "To use screening cardiac troponin (cTn) measurements and electrocardiograms (ECGs) to determine the incidence of elevated cTn and of myocardial infarction (MI) in patients admitted to the intensive care unit (ICU), and to assess whether these findings influence prognosis. This is a prospective screening study. We enrolled consecutive patients admitted to a general medical-surgical ICU over two months. All patients underwent systematic screening with cTn measurements and ECGs on ICU admission, then daily for the first week in ICU, alternate days for up to one month and weekly thereafter until ICU death or discharge, for a maximum of two months. Patients without these investigations ordered during routine clinical care underwent screening for study purposes but these results were unavailable to the ICU team. After the study, all ECGs were interpreted independently in duplicate for ischaemic changes meeting ESC/ACC criteria supporting a diagnosis of MI. Patients were classified as having MI (elevated cTn and ECG evidence supporting diagnosis of MI), elevated cTn only (no ECG evidence supporting diagnosis of MI), or no cTn elevation. One hundred and three patients were admitted to the ICU on 112 occasions. Overall, 37 patients (35.9 per cent) had an MI, 15 patients (14.6 per cent) had an elevated cTn only and 51 patients (49.5 per cent) had no cTn elevation. Patients with MI had longer duration of mechanical ventilation (p < 0.0001), longer ICU stay (p = 0.001), higher ICU mortality (p < 0.0001) and higher hospital mortality (p < 0.0001) compared with those with no cTn elevation. Patients with elevated cTn had higher hospital mortality (p = 0.001) than patients without cTn elevation. Elevated cTn was associated with increased hospital mortality (odds ratio 27.3, 95 per cent CI 1.7 – 449.4), after adjusting for APACHE II score, MI and advanced life support. The ICU team diagnosed 18 patients (17.5 per cent) as having MI on clinical grounds; four of these patients did not have MI by adjudication. Thus, screening detected an additional 23 MIs not diagnosed in practice, reflecting 62.2 per cent of MIs ultimately diagnosed. Patients with MI diagnosed by the ICU team had similar outcomes to patients with MI detected by screening alone. Systematic screening detected elevated cTn measurements and MI in more patients than were found in routine practice. Elevated cTn was an independent predictor of hospital mortality. Further research is needed to evaluate whether screening and subsequent treatment of these patients reduces mortality." @default.
• W2019467771 created "2016-06-24" @default.
• W2019467771 creator A5004328879 @default.
• W2019467771 creator A5015042066 @default.
• W2019467771 creator A5023885688 @default.
• W2019467771 creator A5024226899 @default.
• W2019467771 creator A5051729832 @default.
• W2019467771 creator A5062762288 @default.
• W2019467771 creator A5067825429 @default.
• W2019467771 creator A5079941141 @default.
• W2019467771 creator A5084752934 @default.
• W2019467771 creator A5084919462 @default.
• W2019467771 date "2008-01-01" @default.
• W2019467771 modified "2023-10-15" @default.
• W2019467771 title "Detecting myocardial infarction in critical illness using screening troponin measurements and ECG recordings" @default.
• W2019467771 cites W1935149836 @default.
• W2019467771 cites W1936743100 @default.
• W2019467771 cites W1954558631 @default.
• W2019467771 cites W1968400561 @default.
• W2019467771 cites W1974718993 @default.
• W2019467771 cites W1982516608 @default.
• W2019467771 cites W1991068147 @default.
• W2019467771 cites W2042374378 @default.
• W2019467771 cites W2054312564 @default.
• W2019467771 cites W2138516441 @default.
• W2019467771 cites W2162109366 @default.
• W2019467771 cites W2620550732 @default.
• W2019467771 doi "https://doi.org/10.1186/cc6815" @default.
• W2019467771 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2447557" @default.
• W2019467771 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18318915" @default.
• W2019467771 hasPublicationYear "2008" @default.
• W2019467771 type Work @default.
• W2019467771 sameAs 2019467771 @default.
• W2019467771 citedByCount "39" @default.
• W2019467771 countsByYear W20194677712012 @default.
• W2019467771 countsByYear W20194677712013 @default.
• W2019467771 countsByYear W20194677712014 @default.
• W2019467771 countsByYear W20194677712015 @default.
• W2019467771 countsByYear W20194677712016 @default.
• W2019467771 countsByYear W20194677712018 @default.
• W2019467771 countsByYear W20194677712019 @default.
• W2019467771 crossrefType "journal-article" @default.
• W2019467771 hasAuthorship W2019467771A5004328879 @default.
• W2019467771 hasAuthorship W2019467771A5015042066 @default.
• W2019467771 hasAuthorship W2019467771A5023885688 @default.
• W2019467771 hasAuthorship W2019467771A5024226899 @default.
• W2019467771 hasAuthorship W2019467771A5051729832 @default.
• W2019467771 hasAuthorship W2019467771A5062762288 @default.
• W2019467771 hasAuthorship W2019467771A5067825429 @default.
• W2019467771 hasAuthorship W2019467771A5079941141 @default.
• W2019467771 hasAuthorship W2019467771A5084752934 @default.
• W2019467771 hasAuthorship W2019467771A5084919462 @default.
• W2019467771 hasBestOaLocation W20194677711 @default.
• W2019467771 hasConcept C120665830 @default.
• W2019467771 hasConcept C121332964 @default.
• W2019467771 hasConcept C126322002 @default.
• W2019467771 hasConcept C164705383 @default.
• W2019467771 hasConcept C188816634 @default.
• W2019467771 hasConcept C194828623 @default.
• W2019467771 hasConcept C2776376669 @default.
• W2019467771 hasConcept C36036425 @default.
• W2019467771 hasConcept C500558357 @default.
• W2019467771 hasConcept C61511704 @default.
• W2019467771 hasConcept C71924100 @default.
• W2019467771 hasConceptScore W2019467771C120665830 @default.
• W2019467771 hasConceptScore W2019467771C121332964 @default.
• W2019467771 hasConceptScore W2019467771C126322002 @default.
• W2019467771 hasConceptScore W2019467771C164705383 @default.
• W2019467771 hasConceptScore W2019467771C188816634 @default.
• W2019467771 hasConceptScore W2019467771C194828623 @default.
• W2019467771 hasConceptScore W2019467771C2776376669 @default.
• W2019467771 hasConceptScore W2019467771C36036425 @default.
• W2019467771 hasConceptScore W2019467771C500558357 @default.
• W2019467771 hasConceptScore W2019467771C61511704 @default.
• W2019467771 hasConceptScore W2019467771C71924100 @default.
• W2019467771 hasIssue "2" @default.
• W2019467771 hasLocation W20194677711 @default.
• W2019467771 hasLocation W20194677712 @default.
• W2019467771 hasLocation W20194677713 @default.
• W2019467771 hasLocation W20194677714 @default.
• W2019467771 hasOpenAccess W2019467771 @default.
• W2019467771 hasPrimaryLocation W20194677711 @default.
• W2019467771 hasRelatedWork W2006180981 @default.
• W2019467771 hasRelatedWork W2013156117 @default.
• W2019467771 hasRelatedWork W2026435239 @default.
• W2019467771 hasRelatedWork W2883256220 @default.
• W2019467771 hasRelatedWork W3023271504 @default.
• W2019467771 hasRelatedWork W3031379692 @default.
• W2019467771 hasRelatedWork W3032523068 @default.
• W2019467771 hasRelatedWork W3097606034 @default.
• W2019467771 hasRelatedWork W4382010598 @default.
• W2019467771 hasRelatedWork W4384517648 @default.
• W2019467771 hasVolume "12" @default.
• W2019467771 isParatext "false" @default.
• W2019467771 isRetracted "false" @default.
• W2019467771 magId "2019467771" @default.
• W2019467771 workType "article" @default.