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• W2019468455 abstract "Backgrounds: Narrow band imaging (NBI, Olympus Medical Systems, Co. Ltd.) with magnifying endoscopy (NBI-ME) can yield detailed inspection of true mucosal microstructure and microvascular patterns. NBI-ME is expected to providing a more detailed assessment of the border between normal mucosa and the lesion. On the other hand, endoscopic submucosal dissection (ESD) can allow to resect the intended area accurately. Therefore, the resection with cancer on the lateral margin of the resected specimen (i.e. LM (+) resection) by ESD must be caused by misdiagnosing of the tumor extent. To diagnose the accurate extent of EGC using NBI-ME might increase the resection without cancer on the lateral margin of the resected specimen (i.e. LM (-) resection) rate. Objective: To investigate the improvement of diagnostic accuracy using NBI-ME for tumor lateral extent before ESD for EGC. Design: A retrospective analysis of consecutive patients. Setting: A refferal cancer center. Patients: From July 2005 to June 2006, a total of 452 consecutive EGCs were performed ESD in our center. EGCs existed on the esophago-gastric junction and pylorus ring, resected by piecemeal fashion and performed LM (+) resection with unskilled technique were excluded to eliminate the influence of technical difficulty with ESD. Thus, 415 EGCs were analyzed in this retrospective study. Intervention: The EGCs were carefully observed before ESD to determine the removal area. 139 EGCs were evaluated using chromoendosocopy (CE) with 0.2% indigocarmine alone (CE alone group) and 276 EGCs were evaluated using NBI-ME following CE (NBI-ME group). We compared LM (-) resection rate of ESD between in CE alone group and in NBI-ME group, retrospectively. Main Outcome measurements: LM (-) rate of ESD in CE alone group and NBI-ME group. Results: 9 cases (2.2%) were performed LM (+) resection in all eligible cases. LM (-) resection rates were 97.1% in CE alone group and 98.2% in NBI-ME group. Significant difference was not seen between the two groups (p = 0.73). LM (-) resection rates were almost same in CE alone group (98.5%) and NBI-ME group (98.7%) among the lesion which were detected clearly the tumor extent using CE alone (p = 0.74), but increased in NBI-ME group (96.2%) than in CE alone group (71.4%) among the lesion which were not detected clearly the tumor extent with CE alone (p = 0.07) . Limitation: Uncontrolled retrospective analysis. Conclusion: The assessment of EGC using NBI-ME before ESD provides accurate diagnosis of tumor lateral extent and can increase the LM (-) resection rate in the lesions which are difficult to determine the tumor margin using CE alone." @default.
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• W2019468455 date "2008-04-01" @default.
• W2019468455 modified "2023-09-25" @default.
• W2019468455 title "Is Narrow Band Imaging with Magnifying Endoscopy Useful for the Estimate of Tumor Lateral Extent Before Endoscopic Submucosal Dissection for Early Gastric Cancer? - A Retrospective Analysis Compared with Chromoendoscopy" @default.
• W2019468455 doi "https://doi.org/10.1016/j.gie.2008.03.780" @default.
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