FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2019468723> ?p ?o ?g. }

• W2019468723 endingPage "281" @default.
• W2019468723 startingPage "275" @default.
• W2019468723 abstract "Two alkaline RNases, designated RNase 1 and RNase 2, were isolated from the culture media of silica-treated and non-treated macrophages. The yield of RNase from the medium of silica-treated macrophages was 30% of that from the non-treated control. The effects of these RNases on cultured granuloma fibroblasts and on granulation-tissue nuclei were studied. RNase 1 inhibited thymidine incorporation into fibroblasts except at low concentrations, where it was observed to be stimulatory. RNase 1 also inhibited the protein synthesis of fibroblasts. The incorporation of cytidine into RNA in cultured fibroblasts was not affected by RNase 1, but the incorporation into isolated nuclei was decreased. In pulse chase experiments RNase 1 increased the release of cytidine, but not that of thymidine, from the cells. RNase 2 had no effect on the protein or nucleic acid metabolism of the fibroblasts or on the RNA metabolism of isolated nuclei, perhaps because of impermeability. These experiments confirm that macrophage RNase activity is able to regulate the metabolism of granulation-tissue fibroblasts by increasing RNA degradation. Through this action it also regulates DNA and protein synthesis and other metabolic functions of those cells." @default.
• W2019468723 created "2016-06-24" @default.
• W2019468723 creator A5004480713 @default.
• W2019468723 creator A5028769951 @default.
• W2019468723 creator A5060121749 @default.
• W2019468723 date "1980-07-01" @default.
• W2019468723 modified "2023-10-16" @default.
• W2019468723 title "Effects of purified macrophage RNases on granuloma fibroblasts with reference to silicosis" @default.
• W2019468723 cites W1519956439 @default.
• W2019468723 cites W1585315651 @default.
• W2019468723 cites W1967717304 @default.
• W2019468723 cites W1971779799 @default.
• W2019468723 cites W1976670068 @default.
• W2019468723 cites W1982280290 @default.
• W2019468723 cites W1987992210 @default.
• W2019468723 cites W2006364079 @default.
• W2019468723 cites W2007260332 @default.
• W2019468723 cites W2019189229 @default.
• W2019468723 cites W2028925121 @default.
• W2019468723 cites W2029412662 @default.
• W2019468723 cites W2035389413 @default.
• W2019468723 cites W2046024629 @default.
• W2019468723 cites W2048547733 @default.
• W2019468723 cites W2053453813 @default.
• W2019468723 cites W2070575975 @default.
• W2019468723 cites W2092495204 @default.
• W2019468723 cites W2113665291 @default.
• W2019468723 cites W2136156520 @default.
• W2019468723 cites W2161444009 @default.
• W2019468723 cites W31134339 @default.
• W2019468723 cites W4236799860 @default.
• W2019468723 cites W4245666356 @default.
• W2019468723 cites W84311485 @default.
• W2019468723 doi "https://doi.org/10.1111/j.1748-1716.1980.tb06598.x" @default.
• W2019468723 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6255752" @default.
• W2019468723 hasPublicationYear "1980" @default.
• W2019468723 type Work @default.
• W2019468723 sameAs 2019468723 @default.
• W2019468723 citedByCount "6" @default.
• W2019468723 countsByYear W20194687232014 @default.
• W2019468723 crossrefType "journal-article" @default.
• W2019468723 hasAuthorship W2019468723A5004480713 @default.
• W2019468723 hasAuthorship W2019468723A5028769951 @default.
• W2019468723 hasAuthorship W2019468723A5060121749 @default.
• W2019468723 hasConcept C104317684 @default.
• W2019468723 hasConcept C10879258 @default.
• W2019468723 hasConcept C153911025 @default.
• W2019468723 hasConcept C181199279 @default.
• W2019468723 hasConcept C202751555 @default.
• W2019468723 hasConcept C203014093 @default.
• W2019468723 hasConcept C24107716 @default.
• W2019468723 hasConcept C2776055305 @default.
• W2019468723 hasConcept C2777108182 @default.
• W2019468723 hasConcept C2778976237 @default.
• W2019468723 hasConcept C2779244956 @default.
• W2019468723 hasConcept C2780269544 @default.
• W2019468723 hasConcept C2780381497 @default.
• W2019468723 hasConcept C2781184954 @default.
• W2019468723 hasConcept C3675279 @default.
• W2019468723 hasConcept C54355233 @default.
• W2019468723 hasConcept C552990157 @default.
• W2019468723 hasConcept C55493867 @default.
• W2019468723 hasConcept C67705224 @default.
• W2019468723 hasConcept C81885089 @default.
• W2019468723 hasConcept C86803240 @default.
• W2019468723 hasConceptScore W2019468723C104317684 @default.
• W2019468723 hasConceptScore W2019468723C10879258 @default.
• W2019468723 hasConceptScore W2019468723C153911025 @default.
• W2019468723 hasConceptScore W2019468723C181199279 @default.
• W2019468723 hasConceptScore W2019468723C202751555 @default.
• W2019468723 hasConceptScore W2019468723C203014093 @default.
• W2019468723 hasConceptScore W2019468723C24107716 @default.
• W2019468723 hasConceptScore W2019468723C2776055305 @default.
• W2019468723 hasConceptScore W2019468723C2777108182 @default.
• W2019468723 hasConceptScore W2019468723C2778976237 @default.
• W2019468723 hasConceptScore W2019468723C2779244956 @default.
• W2019468723 hasConceptScore W2019468723C2780269544 @default.
• W2019468723 hasConceptScore W2019468723C2780381497 @default.
• W2019468723 hasConceptScore W2019468723C2781184954 @default.
• W2019468723 hasConceptScore W2019468723C3675279 @default.
• W2019468723 hasConceptScore W2019468723C54355233 @default.
• W2019468723 hasConceptScore W2019468723C552990157 @default.
• W2019468723 hasConceptScore W2019468723C55493867 @default.
• W2019468723 hasConceptScore W2019468723C67705224 @default.
• W2019468723 hasConceptScore W2019468723C81885089 @default.
• W2019468723 hasConceptScore W2019468723C86803240 @default.
• W2019468723 hasIssue "3" @default.
• W2019468723 hasLocation W20194687231 @default.
• W2019468723 hasLocation W20194687232 @default.
• W2019468723 hasOpenAccess W2019468723 @default.
• W2019468723 hasPrimaryLocation W20194687231 @default.
• W2019468723 hasRelatedWork W1963992374 @default.
• W2019468723 hasRelatedWork W1966103612 @default.
• W2019468723 hasRelatedWork W1967274931 @default.
• W2019468723 hasRelatedWork W2019468723 @default.
• W2019468723 hasRelatedWork W2031714377 @default.
• W2019468723 hasRelatedWork W2050971222 @default.
• W2019468723 hasRelatedWork W2085300355 @default.

• next