FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2019469505> ?p ?o ?g. }

• W2019469505 endingPage "1067" @default.
• W2019469505 startingPage "1061" @default.
• W2019469505 abstract "V itiligo is a disorder of pigmentation characterized by the presence of milk-white skin macules. The term vitiligo may have evolved from either the Latin word vitium, meaning fault, or vitelius meaning spotted calf (Kovacs, 1998). Pigment-producing cells (melanocytes) are absent from vitiligo lesions (Le Poole et al, 1993b); their loss represents a key event in the pathogenesis of the disease. Vitiligo lesions can change in size and shape over time and can develop at any age, but in approximately half of all cases the disease onset is before the age of twenty (Lerner, 1959). Clinical presentations include (a) segmental vitiligo, characterized by lesions that occur in a dermatomal, asymmetric distribution (of limited clinical significance); (b) focal vitiligo, characterized by a limited number of small lesions; (c) generalized vitiligo, the most common type of vitiligo, where lesions occur with bilateral, symmetrical distribution; and (d) universal vitiligo, indicating complete or almost complete depigmentation (Mosher et al, 1993). The incidence of this disease varies greatly between populations (from 0.14% to 8.8%), but the worldwide incidence is considered to be between 1% and 2% (Mosher et al, 1993). As well as the enhanced ultraviolet (UV) sensitivity of depigmented spots, vitiligo also is a cosmetically disabling disorder that often leads to psychologic stress (Porter et al, 1979). In addition, due to the occurrence of similar hypopigmented skin lesions in the early phase of leprosy, vitiligo is a true social stigma in countries in which leprosy is endemic. This problem is probably best emphasized by the terminology used in southern India, where vitiligo is known as ven kushtam, meaning “white leprosy” (Mosher et al, 1993). There are three main hypotheses for the pathogenesis of vitiligo: self destruction, neural, and autoimmune (Kovacs, 1998). In a number of recent studies, strong evidence in favor of the autoimmune hypothesis has been obtained. This review will discuss the relevant new evidence for autoimmune melanocyte destruction in vitiligo." @default.
• W2019469505 created "2016-06-24" @default.
• W2019469505 creator A5029094113 @default.
• W2019469505 creator A5030583090 @default.
• W2019469505 creator A5032324734 @default.
• W2019469505 creator A5040845473 @default.
• W2019469505 creator A5051756087 @default.
• W2019469505 date "2001-08-01" @default.
• W2019469505 modified "2023-10-18" @default.
• W2019469505 title "Autoimmune Melanocyte Destruction in Vitiligo" @default.
• W2019469505 cites W1482547394 @default.
• W2019469505 cites W1498880273 @default.
• W2019469505 cites W1525721830 @default.
• W2019469505 cites W1818666962 @default.
• W2019469505 cites W1943542723 @default.
• W2019469505 cites W1944593595 @default.
• W2019469505 cites W1964456881 @default.
• W2019469505 cites W1967290860 @default.
• W2019469505 cites W1968971111 @default.
• W2019469505 cites W1969809230 @default.
• W2019469505 cites W1973153649 @default.
• W2019469505 cites W1973735661 @default.
• W2019469505 cites W1974565005 @default.
• W2019469505 cites W1974845876 @default.
• W2019469505 cites W1975291026 @default.
• W2019469505 cites W1975692389 @default.
• W2019469505 cites W1978310647 @default.
• W2019469505 cites W1979276428 @default.
• W2019469505 cites W1982175857 @default.
• W2019469505 cites W1986765869 @default.
• W2019469505 cites W1993027034 @default.
• W2019469505 cites W2002964171 @default.
• W2019469505 cites W2008279904 @default.
• W2019469505 cites W2010040020 @default.
• W2019469505 cites W2013007269 @default.
• W2019469505 cites W2015294633 @default.
• W2019469505 cites W2015433529 @default.
• W2019469505 cites W2015562865 @default.
• W2019469505 cites W2019086587 @default.
• W2019469505 cites W2019652915 @default.
• W2019469505 cites W2021064604 @default.
• W2019469505 cites W2026089337 @default.
• W2019469505 cites W2030434448 @default.
• W2019469505 cites W2030873144 @default.
• W2019469505 cites W2034167933 @default.
• W2019469505 cites W2035102795 @default.
• W2019469505 cites W2035692562 @default.
• W2019469505 cites W2035878292 @default.
• W2019469505 cites W2036182073 @default.
• W2019469505 cites W2039656950 @default.
• W2019469505 cites W2045146752 @default.
• W2019469505 cites W2051781518 @default.
• W2019469505 cites W2053884582 @default.
• W2019469505 cites W2056418327 @default.
• W2019469505 cites W2056933374 @default.
• W2019469505 cites W2058816846 @default.
• W2019469505 cites W2067183204 @default.
• W2019469505 cites W2067825293 @default.
• W2019469505 cites W2073962547 @default.
• W2019469505 cites W2074895307 @default.
• W2019469505 cites W2079536616 @default.
• W2019469505 cites W2080798807 @default.
• W2019469505 cites W2081044441 @default.
• W2019469505 cites W2087042268 @default.
• W2019469505 cites W2088541521 @default.
• W2019469505 cites W2090135428 @default.
• W2019469505 cites W2094128254 @default.
• W2019469505 cites W2095213901 @default.
• W2019469505 cites W2099410622 @default.
• W2019469505 cites W2101703381 @default.
• W2019469505 cites W2107629538 @default.
• W2019469505 cites W2108108310 @default.
• W2019469505 cites W2116293732 @default.
• W2019469505 cites W2121698961 @default.
• W2019469505 cites W2126614953 @default.
• W2019469505 cites W2126836839 @default.
• W2019469505 cites W2138407913 @default.
• W2019469505 cites W2138959209 @default.
• W2019469505 cites W2144632284 @default.
• W2019469505 cites W2145379300 @default.
• W2019469505 cites W2146600597 @default.
• W2019469505 cites W2147266039 @default.
• W2019469505 cites W2154321097 @default.
• W2019469505 cites W2158119215 @default.
• W2019469505 cites W2158963283 @default.
• W2019469505 cites W2159703967 @default.
• W2019469505 cites W2166554253 @default.
• W2019469505 cites W2167008563 @default.
• W2019469505 cites W2419061442 @default.
• W2019469505 cites W4211196114 @default.
• W2019469505 cites W4241141024 @default.
• W2019469505 cites W4375940934 @default.
• W2019469505 doi "https://doi.org/10.1038/labinvest.3780318" @default.
• W2019469505 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11502857" @default.
• W2019469505 hasPublicationYear "2001" @default.
• W2019469505 type Work @default.
• W2019469505 sameAs 2019469505 @default.
• W2019469505 citedByCount "58" @default.

• next