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- W2019472499 abstract "Abstract The association of free or liposome-entrapped [3H]methotrexate ([3H]MTX) with thioglycollate-elicited macrophages was investigated in-vitro. [14C]Cholesteryl oleate was incorporated into the liposomes as a lipid marker. [3H]MTX association with the macrophages was 5 to 9-fold higher with liposome-entrapped [3H]MTX than with the free drug. Macrophage-liposome association was biphasic, temperature-dependent and saturable at high liposomal lipid concentration. A high liposome cholesterol (CH) content or the presence of 2,4-dinitrophenol or colchicine also reduced macrophage-liposome association." @default.
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- W2019472499 title "Association of Liposome-entrapped [3H]Methotrexate with Thioglycollate-elicited Macrophages In-vitro" @default.
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- W2019472499 doi "https://doi.org/10.1111/j.2042-7158.1988.tb05212.x" @default.
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