FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2019474311> ?p ?o ?g. }

• W2019474311 endingPage "558" @default.
• W2019474311 startingPage "555" @default.
• W2019474311 abstract "In healthy infants, the levels of TSH are known to peak at 50-100 times adult values during the first days of life. In studies of isolated human infant adipocytes, we have earlier shown that bovine TSH (bTSH) has a strong lipolytic effect, accompanied by a blunted response of adipocytes to catecholamines. In this study, we used human recombinant TSH (hTSH), and incubation of adipocytes with hTSH induced a lipolytic response similar to that obtained with the beta-adrenergic receptor agonist isoprenaline in adipocytes isolated from three infants. The lipolytic effect of hTSH was completely blocked by inhibitory TSH receptor (TSHR) antibodies. The TSHR mediates the effects of TSH in the thyroid, and it has been detected in some extrathyroid tissues, but not in isolated human adipocytes or childhood adipose tissue. In this study, we found TSHR RNA in infant and adult adipose tissues and isolated adipocytes with reverse transcriptase-PCR. The sequence of the amplified PCR product agreed with the published sequence. Northern blot hybridization on RNA prepared from infant adipose tissue showed a transcript of the expected size, and the expression of TSHR seemed higher in infant than in adult adipose tissue. In conclusion, this study indicates that TSH plays an active role in the metabolic adaptation after birth." @default.
• W2019474311 created "2016-06-24" @default.
• W2019474311 creator A5020051591 @default.
• W2019474311 creator A5020769883 @default.
• W2019474311 creator A5023070542 @default.
• W2019474311 creator A5059419357 @default.
• W2019474311 date "1998-04-01" @default.
• W2019474311 modified "2023-09-30" @default.
• W2019474311 title "Presence of Thyrotropin Receptor in Infant Adipocytes" @default.
• W2019474311 cites W1964605907 @default.
• W2019474311 cites W1972928539 @default.
• W2019474311 cites W1973414658 @default.
• W2019474311 cites W1976861460 @default.
• W2019474311 cites W1977929190 @default.
• W2019474311 cites W1986642553 @default.
• W2019474311 cites W1990973489 @default.
• W2019474311 cites W1993096445 @default.
• W2019474311 cites W2014595371 @default.
• W2019474311 cites W2019972073 @default.
• W2019474311 cites W2050661862 @default.
• W2019474311 cites W2059953343 @default.
• W2019474311 cites W2063294738 @default.
• W2019474311 cites W2070533629 @default.
• W2019474311 cites W2073133547 @default.
• W2019474311 cites W2091284044 @default.
• W2019474311 cites W2091387819 @default.
• W2019474311 cites W2108670261 @default.
• W2019474311 cites W2136868015 @default.
• W2019474311 cites W2143873575 @default.
• W2019474311 cites W2167850291 @default.
• W2019474311 cites W2338808163 @default.
• W2019474311 cites W2460961443 @default.
• W2019474311 cites W2889617365 @default.
• W2019474311 cites W4229709315 @default.
• W2019474311 cites W4232995558 @default.
• W2019474311 cites W4240811362 @default.
• W2019474311 cites W4252482537 @default.
• W2019474311 cites W4256077873 @default.
• W2019474311 cites W4294216491 @default.
• W2019474311 doi "https://doi.org/10.1203/00006450-199804000-00020" @default.
• W2019474311 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9545014" @default.
• W2019474311 hasPublicationYear "1998" @default.
• W2019474311 type Work @default.
• W2019474311 sameAs 2019474311 @default.
• W2019474311 citedByCount "28" @default.
• W2019474311 countsByYear W20194743112014 @default.
• W2019474311 countsByYear W20194743112015 @default.
• W2019474311 countsByYear W20194743112016 @default.
• W2019474311 countsByYear W20194743112020 @default.
• W2019474311 countsByYear W20194743112021 @default.
• W2019474311 countsByYear W20194743112022 @default.
• W2019474311 crossrefType "journal-article" @default.
• W2019474311 hasAuthorship W2019474311A5020051591 @default.
• W2019474311 hasAuthorship W2019474311A5020769883 @default.
• W2019474311 hasAuthorship W2019474311A5023070542 @default.
• W2019474311 hasAuthorship W2019474311A5059419357 @default.
• W2019474311 hasBestOaLocation W20194743111 @default.
• W2019474311 hasConcept C126322002 @default.
• W2019474311 hasConcept C134018914 @default.
• W2019474311 hasConcept C170493617 @default.
• W2019474311 hasConcept C171089720 @default.
• W2019474311 hasConcept C185592680 @default.
• W2019474311 hasConcept C2776175234 @default.
• W2019474311 hasConcept C2776652619 @default.
• W2019474311 hasConcept C2777608072 @default.
• W2019474311 hasConcept C2778938600 @default.
• W2019474311 hasConcept C526584372 @default.
• W2019474311 hasConcept C71924100 @default.
• W2019474311 hasConcept C86803240 @default.
• W2019474311 hasConceptScore W2019474311C126322002 @default.
• W2019474311 hasConceptScore W2019474311C134018914 @default.
• W2019474311 hasConceptScore W2019474311C170493617 @default.
• W2019474311 hasConceptScore W2019474311C171089720 @default.
• W2019474311 hasConceptScore W2019474311C185592680 @default.
• W2019474311 hasConceptScore W2019474311C2776175234 @default.
• W2019474311 hasConceptScore W2019474311C2776652619 @default.
• W2019474311 hasConceptScore W2019474311C2777608072 @default.
• W2019474311 hasConceptScore W2019474311C2778938600 @default.
• W2019474311 hasConceptScore W2019474311C526584372 @default.
• W2019474311 hasConceptScore W2019474311C71924100 @default.
• W2019474311 hasConceptScore W2019474311C86803240 @default.
• W2019474311 hasIssue "4" @default.
• W2019474311 hasLocation W20194743111 @default.
• W2019474311 hasLocation W20194743112 @default.
• W2019474311 hasOpenAccess W2019474311 @default.
• W2019474311 hasPrimaryLocation W20194743111 @default.
• W2019474311 hasRelatedWork W2017606817 @default.
• W2019474311 hasRelatedWork W2027098794 @default.
• W2019474311 hasRelatedWork W2048359366 @default.
• W2019474311 hasRelatedWork W2049045125 @default.
• W2019474311 hasRelatedWork W2125103862 @default.
• W2019474311 hasRelatedWork W2142749562 @default.
• W2019474311 hasRelatedWork W2228231544 @default.
• W2019474311 hasRelatedWork W2547949331 @default.
• W2019474311 hasRelatedWork W2998970372 @default.
• W2019474311 hasRelatedWork W38646089 @default.
• W2019474311 hasVolume "43" @default.
• W2019474311 isParatext "false" @default.

• next