Matches in SemOpenAlex for { <https://semopenalex.org/work/W2019498116> ?p ?o ?g. }
Showing items 1 to 84 of
84
with 100 items per page.
- W2019498116 abstract "Valproate (VPA) is a teratogenic anticonvulsant (AED), but vitamin supplementation has been suggested to limit the effect of VPA on the fetus. Maternal urinary metabolites were monitored to assess the metabolic effects of VPA before and after vitamin supplementation.A pregnant woman with epilepsy receiving VPA and ethosuximide (ESM) was given high-dose multivitamins from 13 to 28 weeks' gestation. Maternal urinary metabolites were measured throughout the pregnancy by gas chromatography/mass spectrometry.Before multivitamin supplementation began, the patient had significantly increased excretion rates of alpha-ketoglutarate, beta-lactate, pyruvate, lactate, methylmalonate, and other metabolites compared with normal pregnant women. During multivitamin supplementation, many previously increased excretion rates decreased significantly. Fetal head growth was normal up to 30 weeks, but then lagged. Bitemporal narrowing was noted at birth.VPA may cause metabolic abnormalities in pregnancy. Many biochemical abnormalities attributable to VPA in this patient were corrected with high-dose multivitamin supplementation. The specific relation between biochemical abnormalities and VPA teratogenesis remains to be determined." @default.
- W2019498116 created "2016-06-24" @default.
- W2019498116 creator A5011766159 @default.
- W2019498116 creator A5048387327 @default.
- W2019498116 creator A5054369497 @default.
- W2019498116 date "1999-04-01" @default.
- W2019498116 modified "2023-09-25" @default.
- W2019498116 title "Valproate-Induced Biochemical Abnormalities in Pregnancy Corrected by Vitamins: A Case Report" @default.
- W2019498116 cites W1999366195 @default.
- W2019498116 cites W2021502375 @default.
- W2019498116 cites W2029251112 @default.
- W2019498116 cites W2029289710 @default.
- W2019498116 cites W2045147239 @default.
- W2019498116 cites W2055606703 @default.
- W2019498116 cites W2080113362 @default.
- W2019498116 cites W2098709113 @default.
- W2019498116 cites W2168531181 @default.
- W2019498116 cites W2408009577 @default.
- W2019498116 doi "https://doi.org/10.1111/j.1528-1157.1999.tb00750.x" @default.
- W2019498116 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10219281" @default.
- W2019498116 hasPublicationYear "1999" @default.
- W2019498116 type Work @default.
- W2019498116 sameAs 2019498116 @default.
- W2019498116 citedByCount "7" @default.
- W2019498116 crossrefType "journal-article" @default.
- W2019498116 hasAuthorship W2019498116A5011766159 @default.
- W2019498116 hasAuthorship W2019498116A5048387327 @default.
- W2019498116 hasAuthorship W2019498116A5054369497 @default.
- W2019498116 hasConcept C10146269 @default.
- W2019498116 hasConcept C118552586 @default.
- W2019498116 hasConcept C126322002 @default.
- W2019498116 hasConcept C134018914 @default.
- W2019498116 hasConcept C172680121 @default.
- W2019498116 hasConcept C2775858608 @default.
- W2019498116 hasConcept C2776551950 @default.
- W2019498116 hasConcept C2776940978 @default.
- W2019498116 hasConcept C2777172819 @default.
- W2019498116 hasConcept C2777992146 @default.
- W2019498116 hasConcept C2778186239 @default.
- W2019498116 hasConcept C2779234561 @default.
- W2019498116 hasConcept C42407357 @default.
- W2019498116 hasConcept C46973012 @default.
- W2019498116 hasConcept C54355233 @default.
- W2019498116 hasConcept C65290608 @default.
- W2019498116 hasConcept C71924100 @default.
- W2019498116 hasConcept C77411442 @default.
- W2019498116 hasConcept C86803240 @default.
- W2019498116 hasConceptScore W2019498116C10146269 @default.
- W2019498116 hasConceptScore W2019498116C118552586 @default.
- W2019498116 hasConceptScore W2019498116C126322002 @default.
- W2019498116 hasConceptScore W2019498116C134018914 @default.
- W2019498116 hasConceptScore W2019498116C172680121 @default.
- W2019498116 hasConceptScore W2019498116C2775858608 @default.
- W2019498116 hasConceptScore W2019498116C2776551950 @default.
- W2019498116 hasConceptScore W2019498116C2776940978 @default.
- W2019498116 hasConceptScore W2019498116C2777172819 @default.
- W2019498116 hasConceptScore W2019498116C2777992146 @default.
- W2019498116 hasConceptScore W2019498116C2778186239 @default.
- W2019498116 hasConceptScore W2019498116C2779234561 @default.
- W2019498116 hasConceptScore W2019498116C42407357 @default.
- W2019498116 hasConceptScore W2019498116C46973012 @default.
- W2019498116 hasConceptScore W2019498116C54355233 @default.
- W2019498116 hasConceptScore W2019498116C65290608 @default.
- W2019498116 hasConceptScore W2019498116C71924100 @default.
- W2019498116 hasConceptScore W2019498116C77411442 @default.
- W2019498116 hasConceptScore W2019498116C86803240 @default.
- W2019498116 hasLocation W20194981161 @default.
- W2019498116 hasLocation W20194981162 @default.
- W2019498116 hasOpenAccess W2019498116 @default.
- W2019498116 hasPrimaryLocation W20194981161 @default.
- W2019498116 hasRelatedWork W1989351211 @default.
- W2019498116 hasRelatedWork W2000276695 @default.
- W2019498116 hasRelatedWork W2006813420 @default.
- W2019498116 hasRelatedWork W2021555474 @default.
- W2019498116 hasRelatedWork W2021843942 @default.
- W2019498116 hasRelatedWork W2083260458 @default.
- W2019498116 hasRelatedWork W2094082932 @default.
- W2019498116 hasRelatedWork W2463051206 @default.
- W2019498116 hasRelatedWork W3097631522 @default.
- W2019498116 hasRelatedWork W73002945 @default.
- W2019498116 isParatext "false" @default.
- W2019498116 isRetracted "false" @default.
- W2019498116 magId "2019498116" @default.
- W2019498116 workType "article" @default.