Matches in SemOpenAlex for { <https://semopenalex.org/work/W2019508355> ?p ?o ?g. }
Showing items 1 to 90 of
90
with 100 items per page.
- W2019508355 endingPage "203" @default.
- W2019508355 startingPage "193" @default.
- W2019508355 abstract "10−6 and 10−5 M spironolactone decreased the total conversion of 14C-arachidonic acid to 6-keto-prostaglandin (PG) Flα, PGE2 and PGF2α in rat aortic and mesenteric artery rings by 29 and 55% respectively. Same concentrations of spironolactone decreased the total conversion of 14C-arachidonic acid to thromboxane (TX) B2, PGE2 and PGF2α in human platelets by 3 and 21% respectively. These findings provide a possible basis for the significant inhibition by spironolactone of vascular reactivity to norepinephrine. Spironolactone seemed to act in both vascular tissue and platelets to suppress PG synthesis at the prostaglandin endoperoxide synthetase level. This direct action of spironolactone could contribute to its vascular and other effects." @default.
- W2019508355 created "2016-06-24" @default.
- W2019508355 creator A5007381601 @default.
- W2019508355 creator A5019163426 @default.
- W2019508355 date "1980-03-01" @default.
- W2019508355 modified "2023-09-26" @default.
- W2019508355 title "Spironolactone decreases the formation of prostaglandins and related substances from arachidonic acid in rat vascular rings and human platelets" @default.
- W2019508355 cites W1779831530 @default.
- W2019508355 cites W1918829821 @default.
- W2019508355 cites W2002367184 @default.
- W2019508355 cites W2006468989 @default.
- W2019508355 cites W2008574207 @default.
- W2019508355 cites W2010694924 @default.
- W2019508355 cites W2032515062 @default.
- W2019508355 cites W2039613023 @default.
- W2019508355 cites W2044763051 @default.
- W2019508355 cites W2046319511 @default.
- W2019508355 cites W2062592130 @default.
- W2019508355 cites W2064056543 @default.
- W2019508355 cites W2064294111 @default.
- W2019508355 cites W2103596394 @default.
- W2019508355 cites W2124738746 @default.
- W2019508355 cites W2142469386 @default.
- W2019508355 cites W2143265003 @default.
- W2019508355 cites W2168055652 @default.
- W2019508355 cites W2297281347 @default.
- W2019508355 cites W2297956866 @default.
- W2019508355 cites W2319342458 @default.
- W2019508355 cites W2405887662 @default.
- W2019508355 cites W2415982869 @default.
- W2019508355 cites W2415587667 @default.
- W2019508355 doi "https://doi.org/10.1016/0161-4630(80)90082-8" @default.
- W2019508355 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7394062" @default.
- W2019508355 hasPublicationYear "1980" @default.
- W2019508355 type Work @default.
- W2019508355 sameAs 2019508355 @default.
- W2019508355 citedByCount "6" @default.
- W2019508355 crossrefType "journal-article" @default.
- W2019508355 hasAuthorship W2019508355A5007381601 @default.
- W2019508355 hasAuthorship W2019508355A5019163426 @default.
- W2019508355 hasConcept C126322002 @default.
- W2019508355 hasConcept C134018914 @default.
- W2019508355 hasConcept C181199279 @default.
- W2019508355 hasConcept C185592680 @default.
- W2019508355 hasConcept C2776379505 @default.
- W2019508355 hasConcept C2776785769 @default.
- W2019508355 hasConcept C2778078955 @default.
- W2019508355 hasConcept C2778525890 @default.
- W2019508355 hasConcept C2780664492 @default.
- W2019508355 hasConcept C2781080829 @default.
- W2019508355 hasConcept C55493867 @default.
- W2019508355 hasConcept C71924100 @default.
- W2019508355 hasConcept C89560881 @default.
- W2019508355 hasConcept C98274493 @default.
- W2019508355 hasConceptScore W2019508355C126322002 @default.
- W2019508355 hasConceptScore W2019508355C134018914 @default.
- W2019508355 hasConceptScore W2019508355C181199279 @default.
- W2019508355 hasConceptScore W2019508355C185592680 @default.
- W2019508355 hasConceptScore W2019508355C2776379505 @default.
- W2019508355 hasConceptScore W2019508355C2776785769 @default.
- W2019508355 hasConceptScore W2019508355C2778078955 @default.
- W2019508355 hasConceptScore W2019508355C2778525890 @default.
- W2019508355 hasConceptScore W2019508355C2780664492 @default.
- W2019508355 hasConceptScore W2019508355C2781080829 @default.
- W2019508355 hasConceptScore W2019508355C55493867 @default.
- W2019508355 hasConceptScore W2019508355C71924100 @default.
- W2019508355 hasConceptScore W2019508355C89560881 @default.
- W2019508355 hasConceptScore W2019508355C98274493 @default.
- W2019508355 hasIssue "3" @default.
- W2019508355 hasLocation W20195083551 @default.
- W2019508355 hasLocation W20195083552 @default.
- W2019508355 hasOpenAccess W2019508355 @default.
- W2019508355 hasPrimaryLocation W20195083551 @default.
- W2019508355 hasRelatedWork W2000338539 @default.
- W2019508355 hasRelatedWork W2015206361 @default.
- W2019508355 hasRelatedWork W2019508355 @default.
- W2019508355 hasRelatedWork W2071059003 @default.
- W2019508355 hasRelatedWork W2097711288 @default.
- W2019508355 hasRelatedWork W2416303743 @default.
- W2019508355 hasRelatedWork W2440124556 @default.
- W2019508355 hasRelatedWork W4252291428 @default.
- W2019508355 hasRelatedWork W82205484 @default.
- W2019508355 hasRelatedWork W965366625 @default.
- W2019508355 hasVolume "4" @default.
- W2019508355 isParatext "false" @default.
- W2019508355 isRetracted "false" @default.
- W2019508355 magId "2019508355" @default.
- W2019508355 workType "article" @default.