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- W2019529908 abstract "The production process for Arthrobacter simplex high specific hydrocortisone Δ1-dehydrogenase activity and biomass yield (full experimental plan: 1·5 × 1014 experiments). The specific hydrocortisone Δ1-dehydrogenase activity was improved by a vector of 4·5 to 1800 U g−1. With the optimized medium composition in a stirred tank reactor for batch production of A. simplex, a specific hydrocortisone Δ1-dehydrogenase activity of 2000–3000 U g−1 dry biomass was achieved depending on harvest time (previously reported data: 18–37 U g−1)." @default.
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- W2019529908 date "1995-12-01" @default.
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- W2019529908 title "Use of a genetic algorithm in the development of a synthetic growth medium forArthrobacter simplex with high hydrocortisone Δ1-dehydrogenase activity" @default.
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