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- W2019551443 abstract "Here, we explore the established and potential roles for intradermal adipose tissue in communication with hair follicle biology. The hair follicle delves deep into the rich dermal macroenvironment as it grows to maturity where it is surrounded by large lipid-filled adipocytes. Intradermal adipocytes regenerate with faster kinetics than other adipose tissue depots and in parallel with the hair cycle, suggesting an interplay exists between hair follicle cells and adipocytes. While adipocytes have well-established roles in metabolism and energy storage, until recently, they were overlooked as niche cells that provide important growth signals to neighbouring skin cells. We discuss recent data supporting adipocytes as niche cells for the skin and skin pathologies that may be related to alterations in skin adipose tissue defects." @default.
- W2019551443 created "2016-06-24" @default.
- W2019551443 creator A5020153964 @default.
- W2019551443 creator A5040295525 @default.
- W2019551443 date "2012-09-03" @default.
- W2019551443 modified "2023-10-16" @default.
- W2019551443 title "Unravelling hair follicle-adipocyte communication" @default.
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- W2019551443 doi "https://doi.org/10.1111/exd.12001" @default.
- W2019551443 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3507425" @default.
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