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- W2019553610 abstract "Introduction: Gene therapy protocols have thus far been unable to treat conditions where it is vital that all diseased cells are reached by the therapy. This inability is mainly caused by the inefficiency of gene therapy vectors; simply too few cells actually receive the transgene. Replicating viruses do spread, and cancer gene therapy using replication competent viruses has shown promising successes, although the safety of these vectors remains one of the main concerns. Moreover, as replicating vectors usually destroy the infected cells, this strategy will find limited use outside of the cancer field." @default.
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- W2019553610 date "2005-05-01" @default.
- W2019553610 modified "2023-09-26" @default.
- W2019553610 title "753. Efficient Gene Therapy by Intercellular Spread and Specific Internalization of the Transgene Product" @default.
- W2019553610 doi "https://doi.org/10.1016/j.ymthe.2005.07.294" @default.
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