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- W2019554093 abstract "Aim . The aim of this study was to evaluate the presence of the cytokines tumor necrosis factor-alpha (TNF-<mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML id=E1><mml:mi>α</mml:mi></mml:math>) and interleukin-6 (IL-6) in human periapical lesions. Subjects and methods . Samples were obtained from three groups of teeth: symptomatic teeth, asymptomatic lesions, and uninflamed periradicular tissues as a control. Results . TNF-alpha levels were significantly increased in symptomatic lesions compared to control. Group with asymptomatic lesions had significantly higher concentrations compared to control. There were no significant differences in TNF-alpha levels between symptomatic and asymptomatic lesions. In group with symptomatic lesions, IL-6 levels were significantly higher than in group with asymptomatic lesions. The IL-6 levels in symptomatic group also showed significantly higher concentration in comparison with control group. In asymptomatic group, the IL-6 level had significantly higher concentrations compared to control. Conclusion . These results indicate that symptomatic lesions represent an immunologically active stage of disease, and asymptomatic lesions are the point from which the process advances toward healing." @default.
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- W2019554093 date "2007-01-01" @default.
- W2019554093 modified "2023-10-18" @default.
- W2019554093 title "Tumor Necrosis Factor-Alpha and Interleukin 6 in Human Periapical Lesions" @default.
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- W2019554093 doi "https://doi.org/10.1155/2007/38210" @default.
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