Matches in SemOpenAlex for { <https://semopenalex.org/work/W2019576136> ?p ?o ?g. }
Showing items 1 to 81 of
81
with 100 items per page.
- W2019576136 endingPage "253" @default.
- W2019576136 startingPage "249" @default.
- W2019576136 abstract "The objective of this study was to investigate the effect of a lysine biosynthesis insertion mutation on the growth response and phenotype of Escherichia coli. The lysA gene encodes the last enzyme in the lysine biosynthetic pathway in most bacteria. This E. coli insertion mutant exhibited altered growth physiology and phenotype of the recipient E. coli. The constructed mutant could grow in the absence of lysine supplementation although the extent of growth after 7 h incubation in the presence of most lysine concentration was significantly (p<0.05) decreased compared to that observed with the parent E. coli strain. The mutant was also less able to utilize carbon and nitrogen substrates than the parent E. coli strain as determined by using phenotype arrays. These results suggest that the carbon and nitrogen phenotype profiles of E. coli when measured on phenotype arrays are altered after targeted insertion mutagenesis in the lysA gene. Creation of altered phenotypes may have potential for pharmaceutical and biotechnological applications of lysine E. coli metabolism." @default.
- W2019576136 created "2016-06-24" @default.
- W2019576136 creator A5074848128 @default.
- W2019576136 creator A5088465378 @default.
- W2019576136 date "2003-09-01" @default.
- W2019576136 modified "2023-10-14" @default.
- W2019576136 title "Characterization of an Escherichia coli lysA insertion targeted mutant using phenotype arrays" @default.
- W2019576136 cites W1491764194 @default.
- W2019576136 cites W1511379347 @default.
- W2019576136 cites W1574326311 @default.
- W2019576136 cites W1591161572 @default.
- W2019576136 cites W1726174962 @default.
- W2019576136 cites W1967800612 @default.
- W2019576136 cites W1984852783 @default.
- W2019576136 cites W1998247911 @default.
- W2019576136 cites W2030704598 @default.
- W2019576136 cites W2054324387 @default.
- W2019576136 cites W2068215055 @default.
- W2019576136 cites W2083947314 @default.
- W2019576136 cites W2099190297 @default.
- W2019576136 cites W2126701383 @default.
- W2019576136 cites W2127735177 @default.
- W2019576136 doi "https://doi.org/10.1016/s0960-8524(03)00072-5" @default.
- W2019576136 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12798115" @default.
- W2019576136 hasPublicationYear "2003" @default.
- W2019576136 type Work @default.
- W2019576136 sameAs 2019576136 @default.
- W2019576136 citedByCount "2" @default.
- W2019576136 countsByYear W20195761362013 @default.
- W2019576136 countsByYear W20195761362018 @default.
- W2019576136 crossrefType "journal-article" @default.
- W2019576136 hasAuthorship W2019576136A5074848128 @default.
- W2019576136 hasAuthorship W2019576136A5088465378 @default.
- W2019576136 hasConcept C104317684 @default.
- W2019576136 hasConcept C105702510 @default.
- W2019576136 hasConcept C127716648 @default.
- W2019576136 hasConcept C143065580 @default.
- W2019576136 hasConcept C16318435 @default.
- W2019576136 hasConcept C207583985 @default.
- W2019576136 hasConcept C2776016237 @default.
- W2019576136 hasConcept C2778022156 @default.
- W2019576136 hasConcept C501734568 @default.
- W2019576136 hasConcept C515207424 @default.
- W2019576136 hasConcept C547475151 @default.
- W2019576136 hasConcept C55493867 @default.
- W2019576136 hasConcept C86803240 @default.
- W2019576136 hasConceptScore W2019576136C104317684 @default.
- W2019576136 hasConceptScore W2019576136C105702510 @default.
- W2019576136 hasConceptScore W2019576136C127716648 @default.
- W2019576136 hasConceptScore W2019576136C143065580 @default.
- W2019576136 hasConceptScore W2019576136C16318435 @default.
- W2019576136 hasConceptScore W2019576136C207583985 @default.
- W2019576136 hasConceptScore W2019576136C2776016237 @default.
- W2019576136 hasConceptScore W2019576136C2778022156 @default.
- W2019576136 hasConceptScore W2019576136C501734568 @default.
- W2019576136 hasConceptScore W2019576136C515207424 @default.
- W2019576136 hasConceptScore W2019576136C547475151 @default.
- W2019576136 hasConceptScore W2019576136C55493867 @default.
- W2019576136 hasConceptScore W2019576136C86803240 @default.
- W2019576136 hasIssue "3" @default.
- W2019576136 hasLocation W20195761361 @default.
- W2019576136 hasLocation W20195761362 @default.
- W2019576136 hasOpenAccess W2019576136 @default.
- W2019576136 hasPrimaryLocation W20195761361 @default.
- W2019576136 hasRelatedWork W1530132378 @default.
- W2019576136 hasRelatedWork W1565901822 @default.
- W2019576136 hasRelatedWork W1981142562 @default.
- W2019576136 hasRelatedWork W2019576136 @default.
- W2019576136 hasRelatedWork W2026050814 @default.
- W2019576136 hasRelatedWork W2032247992 @default.
- W2019576136 hasRelatedWork W2130733794 @default.
- W2019576136 hasRelatedWork W2162656176 @default.
- W2019576136 hasRelatedWork W3208418092 @default.
- W2019576136 hasRelatedWork W4284892098 @default.
- W2019576136 hasVolume "89" @default.
- W2019576136 isParatext "false" @default.
- W2019576136 isRetracted "false" @default.
- W2019576136 magId "2019576136" @default.
- W2019576136 workType "article" @default.