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- W2019596688 abstract "The composition and physical state of membrane lipids determine the dynamic nature of membranes, which in turn, could directly be linked to the activity of various membrane-associated cellular functions. To better understand the molecular basis of different membrane-related phenomena we established a novel strategy to alter unsaturation of mammalian cell membranes with an identical genetic background. We transfected L929 mouse fibroblastoid cells with DNA constructs containing the Delta9-fatty acid desaturase gene (Ole1) of S. cerevisiae under the control of desaturase promoters derived either from wild type or mutant strains of the dimorphic fungus H. capsulatum." @default.
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- W2019596688 date "1997-08-01" @default.
- W2019596688 modified "2023-10-14" @default.
- W2019596688 title "Modulation of Lipid Unsaturation and Membrane Fluid State in Mammalian Cells by Stable Transformation with the Δ9-Desaturase Gene ofSaccharomyces cerevisiae" @default.
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- W2019596688 doi "https://doi.org/10.1006/bbrc.1997.7141" @default.
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