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Matches in SemOpenAlex for { <https://semopenalex.org/work/W2019601873> ?p ?o ?g. }

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• W2019601873 abstract "1 By using a specific sensitive stable-isotope dilution gas chromatography-mass spectrometry (GC-MS) assay, hydrazine was detected in the plasma of eight healthy male volunteer subjects taking isoniazid (300 mg daily) for 2 weeks. 2 Accumulation of hydrazine occurred in slow-acetylator phenotypes. 3 Hydrazine was also detected in the plasma of eight out of 14 hypertensive patients treated chronically with hydralazine (200 mg daily). 4 However, the concentrations of hydrazine observed were much lower than in the isoniazid study and were close to the limit of detection. 5 As hydrazine is hepatotoxic, mutagenic and carcinogenic in animals, its presence in human plasma has important toxicological implications." @default.
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• W2019601873 date "1985-03-01" @default.
• W2019601873 modified "2023-09-24" @default.
• W2019601873 title "Plasma Hydrazine Concentrations in Man after Isoniazid and Hydralazine Administration" @default.
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• W2019601873 doi "https://doi.org/10.1177/096032718500400210" @default.
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