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- W2019604807 abstract "Ghrelin and its receptor, growth hormone secretagogue receptor (GHS-R), are produced by various cell types and affect feeding behavior, metabolic regulation, and energy balance. In the mammalian pancreas, the types of endocrine cells immunoreactive for ghrelin vary. Further, no study has clarified the type of endocrine cells producing ghrelin and GHS-R in the non-mammalian pancreas. We immunohistochemically investigated ghrelin-like and GHS-R-like immunoreactivities in the Xenopus pancreas. Ghrelin-immunoreactive cells were observed both in islets and extrainsular regions, and they corresponded to insulin-containing cells. GHS-R-immunoreactive cells were observed in the islets, and these immunoreactive cells corresponded to insulin- and somatostatin-containing cells. These observations suggest that ghrelin is co-secreted with insulin and that ghrelin may act in an autocrine fashion for insulin-containing cells and in a paracrine fashion for somatostatin-containing cells in this species." @default.
- W2019604807 created "2016-06-24" @default.
- W2019604807 creator A5000649789 @default.
- W2019604807 creator A5048128452 @default.
- W2019604807 date "2011-08-01" @default.
- W2019604807 modified "2023-09-25" @default.
- W2019604807 title "Ghrelin- and growth hormone secretagogue receptor-immunoreactive cells in Xenopus pancreas" @default.
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- W2019604807 doi "https://doi.org/10.1016/j.regpep.2011.04.002" @default.
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