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- W2019606989 abstract "Abstract 1. 1. Neurotensin-like immunoreactivity is associated with a subpopulation of multistratified amacrine cells situated in the inner nuclear and plexiform layers of the chick retina. 2. 2. HPLC and radioimmunoassay have shown that the neurotensin immunoreactive material in the chick retina is similar to neurotensin 1–13 , previously identified in bovine and human tissues. 3. 3. Isolated chick retina does not take up 3 H or 125 I-labelled neurotensin, as revealed by autoradiography. 4. 4. By increasing the external K + -concentration, it was shown that the release of endogenous neurotensin from the retina was stimulated. This release is Ca 2− -dependent. 5. 5. The binding of [ 3 H]neurotensin to crude membrane preparations of chick retina was saturable and revealed a single population of binding sites with a K d - value of 3.4 nM and a B max of 115 pmol/g protein. The characteristics of these binding sites suggest the presence of neurotensin receptors. 6. 6. It is proposed that neurotensin is a likely transmitter in the avian retina." @default.
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- W2019606989 title "Neurotensin in the retina: Identification, release and receptor analysis" @default.
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- W2019606989 doi "https://doi.org/10.1016/0197-0186(86)90029-x" @default.
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