Matches in SemOpenAlex for { <https://semopenalex.org/work/W2019626263> ?p ?o ?g. }
- W2019626263 endingPage "1125" @default.
- W2019626263 startingPage "1123" @default.
- W2019626263 abstract "Collagen turnover and cell migration are fundamental aspects of arterial restructuring. To identify mRNAs involved in blood flow-induced arterial restructuring, we performed subtraction polymerase chain reaction and found expression of haptoglobin mRNA in adventitial fibroblasts of rabbit arteries. Haptoglobin is highly expressed in liver, but its arterial expression and function are unknown. In vitro studies revealed that stimulation of haptoglobin expression by lipopolysaccharides in mice fibroblasts stimulated migration of wild-type fibroblasts but had no effect on migration of haptoglobin knockout fibroblasts. In vivo studies showed that flow-induced arterial restructuring was delayed in haptoglobin knockout mice. This new function of haptoglobin might be explained by facilitating cell migration through accumulation of a temporary gelatin matrix because cell culture showed that haptoglobin is involved in the breakdown of gelatin. We conclude that haptoglobin is highly expressed in arterial tissue and is involved in arterial restructuring. This new haptoglobin function may also apply to other functional and pathological restructuring processes such as angiogenesis, tissue repair, and tumor cell invasion." @default.
- W2019626263 created "2016-06-24" @default.
- W2019626263 creator A5013899773 @default.
- W2019626263 creator A5020307262 @default.
- W2019626263 creator A5026850740 @default.
- W2019626263 creator A5038272951 @default.
- W2019626263 creator A5061210616 @default.
- W2019626263 creator A5065971022 @default.
- W2019626263 creator A5071760526 @default.
- W2019626263 creator A5072491065 @default.
- W2019626263 creator A5075583995 @default.
- W2019626263 date "2002-05-21" @default.
- W2019626263 modified "2023-10-02" @default.
- W2019626263 title "Acute‐phase protein haptoglobin is a cell migration factor involved in arterial restructuring" @default.
- W2019626263 cites W1212631268 @default.
- W2019626263 cites W1535567348 @default.
- W2019626263 cites W1691131273 @default.
- W2019626263 cites W1872434980 @default.
- W2019626263 cites W1970803892 @default.
- W2019626263 cites W1970910187 @default.
- W2019626263 cites W1984561531 @default.
- W2019626263 cites W1984804049 @default.
- W2019626263 cites W1988407735 @default.
- W2019626263 cites W2003517508 @default.
- W2019626263 cites W2012016560 @default.
- W2019626263 cites W2016484384 @default.
- W2019626263 cites W2019862823 @default.
- W2019626263 cites W2025328716 @default.
- W2019626263 cites W2032440984 @default.
- W2019626263 cites W2041456436 @default.
- W2019626263 cites W2043605903 @default.
- W2019626263 cites W2063276829 @default.
- W2019626263 cites W2071138105 @default.
- W2019626263 cites W2074297244 @default.
- W2019626263 cites W2076345713 @default.
- W2019626263 cites W2089579393 @default.
- W2019626263 cites W2091979794 @default.
- W2019626263 cites W2094382824 @default.
- W2019626263 cites W2096353669 @default.
- W2019626263 cites W2136649364 @default.
- W2019626263 cites W2161952636 @default.
- W2019626263 cites W2167742884 @default.
- W2019626263 cites W2317358310 @default.
- W2019626263 cites W2324841714 @default.
- W2019626263 doi "https://doi.org/10.1096/fj.02-0019fje" @default.
- W2019626263 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12039846" @default.
- W2019626263 hasPublicationYear "2002" @default.
- W2019626263 type Work @default.
- W2019626263 sameAs 2019626263 @default.
- W2019626263 citedByCount "93" @default.
- W2019626263 countsByYear W20196262632012 @default.
- W2019626263 countsByYear W20196262632013 @default.
- W2019626263 countsByYear W20196262632014 @default.
- W2019626263 countsByYear W20196262632015 @default.
- W2019626263 countsByYear W20196262632016 @default.
- W2019626263 countsByYear W20196262632017 @default.
- W2019626263 countsByYear W20196262632018 @default.
- W2019626263 countsByYear W20196262632019 @default.
- W2019626263 countsByYear W20196262632020 @default.
- W2019626263 countsByYear W20196262632021 @default.
- W2019626263 countsByYear W20196262632022 @default.
- W2019626263 crossrefType "journal-article" @default.
- W2019626263 hasAuthorship W2019626263A5013899773 @default.
- W2019626263 hasAuthorship W2019626263A5020307262 @default.
- W2019626263 hasAuthorship W2019626263A5026850740 @default.
- W2019626263 hasAuthorship W2019626263A5038272951 @default.
- W2019626263 hasAuthorship W2019626263A5061210616 @default.
- W2019626263 hasAuthorship W2019626263A5065971022 @default.
- W2019626263 hasAuthorship W2019626263A5071760526 @default.
- W2019626263 hasAuthorship W2019626263A5072491065 @default.
- W2019626263 hasAuthorship W2019626263A5075583995 @default.
- W2019626263 hasConcept C134018914 @default.
- W2019626263 hasConcept C142724271 @default.
- W2019626263 hasConcept C153911025 @default.
- W2019626263 hasConcept C185592680 @default.
- W2019626263 hasConcept C203014093 @default.
- W2019626263 hasConcept C206396517 @default.
- W2019626263 hasConcept C71924100 @default.
- W2019626263 hasConcept C86803240 @default.
- W2019626263 hasConcept C95444343 @default.
- W2019626263 hasConceptScore W2019626263C134018914 @default.
- W2019626263 hasConceptScore W2019626263C142724271 @default.
- W2019626263 hasConceptScore W2019626263C153911025 @default.
- W2019626263 hasConceptScore W2019626263C185592680 @default.
- W2019626263 hasConceptScore W2019626263C203014093 @default.
- W2019626263 hasConceptScore W2019626263C206396517 @default.
- W2019626263 hasConceptScore W2019626263C71924100 @default.
- W2019626263 hasConceptScore W2019626263C86803240 @default.
- W2019626263 hasConceptScore W2019626263C95444343 @default.
- W2019626263 hasFunder F4320321800 @default.
- W2019626263 hasIssue "9" @default.
- W2019626263 hasLocation W20196262631 @default.
- W2019626263 hasLocation W20196262632 @default.
- W2019626263 hasOpenAccess W2019626263 @default.
- W2019626263 hasPrimaryLocation W20196262631 @default.
- W2019626263 hasRelatedWork W111482683 @default.
- W2019626263 hasRelatedWork W1985013537 @default.
- W2019626263 hasRelatedWork W2004197512 @default.