FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2019628123> ?p ?o ?g. }

• W2019628123 endingPage "5331" @default.
• W2019628123 startingPage "5326" @default.
• W2019628123 abstract "As well as inducing a protective immune response against reinfection, acute measles is associated with a marked suppression of immune functions against superinfecting agents and recall antigens, and this association is the major cause of the current high morbidity and mortality rate associated with measles virus (MV) infections. Dendritic cells (DCs) are antigen-presenting cells crucially involved in the initiation of primary and secondary immune responses, so we set out to define the interaction of MV with these cells. We found that both mature and precursor human DCs generated from peripheral blood monocytic cells express the major MV protein receptor CD46 and are highly susceptible to infection with both MV vaccine (ED) and wild-type (WTF) strains, albeit with different kinetics. Except for the down-regulation of CD46, the expression pattern of functionally important surface antigens on mature DCs was not markedly altered after MV infection. However, precursor DCs up-regulated HLA-DR, CD83, and CD86 within 24 h of WTF infection and 72 h after ED infection, indicating their functional maturation. In addition, interleukin 12 synthesis was markedly enhanced after both ED and WTF infection in DCs. On the other hand, MV-infected DCs strongly interfered with mitogen-dependent proliferation of freshly isolated peripheral blood lymphocytes in vitro. These data indicate that the differentiation of effector functions of DCs is not impaired but rather is stimulated by MV infection. Yet, mature, activated DCs expressing MV surface antigens do give a negative signal to inhibit lymphocyte proliferation and thus contribute to MV-induced immunosuppression." @default.
• W2019628123 created "2016-06-24" @default.
• W2019628123 creator A5013402135 @default.
• W2019628123 creator A5018796363 @default.
• W2019628123 creator A5020039953 @default.
• W2019628123 creator A5031055272 @default.
• W2019628123 creator A5058654280 @default.
• W2019628123 creator A5077110770 @default.
• W2019628123 date "1997-05-13" @default.
• W2019628123 modified "2023-10-13" @default.
• W2019628123 title "Induction of maturation of human blood dendritic cell precursors by measles virus is associated with immunosuppression" @default.
• W2019628123 cites W1506303504 @default.
• W2019628123 cites W1573108532 @default.
• W2019628123 cites W1591089170 @default.
• W2019628123 cites W1845094941 @default.
• W2019628123 cites W1853600630 @default.
• W2019628123 cites W1866642200 @default.
• W2019628123 cites W1924315656 @default.
• W2019628123 cites W1933750471 @default.
• W2019628123 cites W1946374433 @default.
• W2019628123 cites W1970723931 @default.
• W2019628123 cites W1984135202 @default.
• W2019628123 cites W1984933263 @default.
• W2019628123 cites W1991640158 @default.
• W2019628123 cites W1996361962 @default.
• W2019628123 cites W2015507362 @default.
• W2019628123 cites W2022459226 @default.
• W2019628123 cites W2028092080 @default.
• W2019628123 cites W2037796326 @default.
• W2019628123 cites W2042288895 @default.
• W2019628123 cites W2043117600 @default.
• W2019628123 cites W2057294813 @default.
• W2019628123 cites W2058026156 @default.
• W2019628123 cites W2069929656 @default.
• W2019628123 cites W2075847325 @default.
• W2019628123 cites W2077918228 @default.
• W2019628123 cites W2089506255 @default.
• W2019628123 cites W2098767281 @default.
• W2019628123 cites W2100475725 @default.
• W2019628123 cites W2105127582 @default.
• W2019628123 cites W2108473659 @default.
• W2019628123 cites W2112220791 @default.
• W2019628123 cites W2112478558 @default.
• W2019628123 cites W2126394870 @default.
• W2019628123 cites W2142270544 @default.
• W2019628123 cites W2144749899 @default.
• W2019628123 cites W2160157197 @default.
• W2019628123 cites W2177327503 @default.
• W2019628123 cites W2246080810 @default.
• W2019628123 cites W2340679018 @default.
• W2019628123 cites W337453122 @default.
• W2019628123 cites W4252468234 @default.
• W2019628123 doi "https://doi.org/10.1073/pnas.94.10.5326" @default.
• W2019628123 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/24677" @default.
• W2019628123 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9144236" @default.
• W2019628123 hasPublicationYear "1997" @default.
• W2019628123 type Work @default.
• W2019628123 sameAs 2019628123 @default.
• W2019628123 citedByCount "179" @default.
• W2019628123 countsByYear W20196281232012 @default.
• W2019628123 countsByYear W20196281232013 @default.
• W2019628123 countsByYear W20196281232014 @default.
• W2019628123 countsByYear W20196281232015 @default.
• W2019628123 countsByYear W20196281232016 @default.
• W2019628123 countsByYear W20196281232017 @default.
• W2019628123 countsByYear W20196281232018 @default.
• W2019628123 countsByYear W20196281232019 @default.
• W2019628123 countsByYear W20196281232020 @default.
• W2019628123 countsByYear W20196281232021 @default.
• W2019628123 countsByYear W20196281232022 @default.
• W2019628123 crossrefType "journal-article" @default.
• W2019628123 hasAuthorship W2019628123A5013402135 @default.
• W2019628123 hasAuthorship W2019628123A5018796363 @default.
• W2019628123 hasAuthorship W2019628123A5020039953 @default.
• W2019628123 hasAuthorship W2019628123A5031055272 @default.
• W2019628123 hasAuthorship W2019628123A5058654280 @default.
• W2019628123 hasAuthorship W2019628123A5077110770 @default.
• W2019628123 hasBestOaLocation W20196281231 @default.
• W2019628123 hasConcept C147483822 @default.
• W2019628123 hasConcept C159047783 @default.
• W2019628123 hasConcept C203014093 @default.
• W2019628123 hasConcept C22070199 @default.
• W2019628123 hasConcept C2776090121 @default.
• W2019628123 hasConcept C2776438120 @default.
• W2019628123 hasConcept C2778170410 @default.
• W2019628123 hasConcept C2778199166 @default.
• W2019628123 hasConcept C2780252810 @default.
• W2019628123 hasConcept C2781101188 @default.
• W2019628123 hasConcept C86803240 @default.
• W2019628123 hasConcept C8891405 @default.
• W2019628123 hasConceptScore W2019628123C147483822 @default.
• W2019628123 hasConceptScore W2019628123C159047783 @default.
• W2019628123 hasConceptScore W2019628123C203014093 @default.
• W2019628123 hasConceptScore W2019628123C22070199 @default.
• W2019628123 hasConceptScore W2019628123C2776090121 @default.
• W2019628123 hasConceptScore W2019628123C2776438120 @default.
• W2019628123 hasConceptScore W2019628123C2778170410 @default.
• W2019628123 hasConceptScore W2019628123C2778199166 @default.

• next