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- W2019631982 abstract "We show that a single presentation of a zebra finch song, 2 s in duration, will induce an immediate-early gene response in the caudomedial neostriatum of zebra finches (Poephila guttata). Repetition of this stimulus 10 times is sufficient to induce a maximal increase in RNA and protein, detected 30 and 90 min later respectively. Thus very brief stimuli can set in motion a slow genomic process in the brain which takes hours to resolve. Immediate-early gene function is often considered in the context of a feedback model (i.e., to consolidate memories of the inducing event). However, based on the long lag observed here between initiation and full expression of the molecular response, we suggest an alternative, ethologically based, feed-forward model in which exposure to a novel or significant context triggers an increase in the efficiency of memory capture processes for subsequent experiences." @default.
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- W2019631982 date "2000-11-01" @default.
- W2019631982 modified "2023-10-14" @default.
- W2019631982 title "Minimal Experience Required for Immediate-Early Gene Induction in Zebra Finch Neostriatum" @default.
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- W2019631982 doi "https://doi.org/10.1006/nlme.2000.3968" @default.
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