Matches in SemOpenAlex for { <https://semopenalex.org/work/W2019644114> ?p ?o ?g. }
Showing items 1 to 95 of
95
with 100 items per page.
- W2019644114 endingPage "318" @default.
- W2019644114 startingPage "307" @default.
- W2019644114 abstract "Normal and autoimmune mice were studied with regard to signals eliciting differentiation and division of bone marrow stem cells. The erythropoiesis induced by anemia following serial bleedings was analyzed in young autoimmune New Zealand Black (NZB) mice and non-autoimmune strains. No difference in the response to the stimulus created by anemia was noted between the strains. After serial bleedings as a stimulus to stem cell proliferation, a five-fold increase in numbers of proliferating spleen cells occurred in both NZB and DBA/2 strains; the increased proliferating spleen cells in both strains were non-lymphoid. The bled animals had decreased percentages of B cells. The production of autoantibodies was not significantly altered by the experimentally induced anemia. In contrast, anti-immunoglobulin activation of resting B cells was increased in response to anemia. Young mice which had experimentally induced anemia had several characteristics in common with old autoimmune NZB mice. Both old NZB mice and young anemic animals had splenomegaly, increased numbers of proliferating spleen cells, decrease in splenic Ly 5+ cells and an increase in splenic colony forming units (CFUs). The anemic normal strains of animals lacked other characteristics of old NZB mice such as hyperimmunoglobulinemia or autoantibody production or elevated CD5+B cell numbers. This work supports the concept that the increase in spleen cell number, proliferating spleen cells, CFUs and the increased percentages of non-Ly-5 cells (which include erythroid precursors) found in the spleens of old NZB mice may in part result from their autoimmune hemolytic anemia." @default.
- W2019644114 created "2016-06-24" @default.
- W2019644114 creator A5012341652 @default.
- W2019644114 creator A5022445392 @default.
- W2019644114 creator A5061615855 @default.
- W2019644114 creator A5062224091 @default.
- W2019644114 creator A5091859386 @default.
- W2019644114 date "1990-01-01" @default.
- W2019644114 modified "2023-09-24" @default.
- W2019644114 title "Effects of Induced Anemia in Normal and Autoimmune Mice" @default.
- W2019644114 cites W1604823479 @default.
- W2019644114 cites W1624485603 @default.
- W2019644114 cites W1977845150 @default.
- W2019644114 cites W1982034147 @default.
- W2019644114 cites W1983287618 @default.
- W2019644114 cites W1985928819 @default.
- W2019644114 cites W2033871610 @default.
- W2019644114 cites W2035600485 @default.
- W2019644114 cites W2064498617 @default.
- W2019644114 cites W2070437307 @default.
- W2019644114 cites W2078190100 @default.
- W2019644114 cites W2086052231 @default.
- W2019644114 cites W2096431565 @default.
- W2019644114 cites W2106916231 @default.
- W2019644114 cites W2144225361 @default.
- W2019644114 cites W2165989331 @default.
- W2019644114 cites W2169790726 @default.
- W2019644114 cites W2227157639 @default.
- W2019644114 doi "https://doi.org/10.3109/08820139009050772" @default.
- W2019644114 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2210804" @default.
- W2019644114 hasPublicationYear "1990" @default.
- W2019644114 type Work @default.
- W2019644114 sameAs 2019644114 @default.
- W2019644114 citedByCount "2" @default.
- W2019644114 countsByYear W20196441142014 @default.
- W2019644114 crossrefType "journal-article" @default.
- W2019644114 hasAuthorship W2019644114A5012341652 @default.
- W2019644114 hasAuthorship W2019644114A5022445392 @default.
- W2019644114 hasAuthorship W2019644114A5061615855 @default.
- W2019644114 hasAuthorship W2019644114A5062224091 @default.
- W2019644114 hasAuthorship W2019644114A5091859386 @default.
- W2019644114 hasConcept C109159458 @default.
- W2019644114 hasConcept C126322002 @default.
- W2019644114 hasConcept C134018914 @default.
- W2019644114 hasConcept C159654299 @default.
- W2019644114 hasConcept C163764329 @default.
- W2019644114 hasConcept C203014093 @default.
- W2019644114 hasConcept C2777385706 @default.
- W2019644114 hasConcept C2778248108 @default.
- W2019644114 hasConcept C2778453870 @default.
- W2019644114 hasConcept C2779703530 @default.
- W2019644114 hasConcept C2780007613 @default.
- W2019644114 hasConcept C2780931953 @default.
- W2019644114 hasConcept C28328180 @default.
- W2019644114 hasConcept C71924100 @default.
- W2019644114 hasConcept C86803240 @default.
- W2019644114 hasConcept C95444343 @default.
- W2019644114 hasConceptScore W2019644114C109159458 @default.
- W2019644114 hasConceptScore W2019644114C126322002 @default.
- W2019644114 hasConceptScore W2019644114C134018914 @default.
- W2019644114 hasConceptScore W2019644114C159654299 @default.
- W2019644114 hasConceptScore W2019644114C163764329 @default.
- W2019644114 hasConceptScore W2019644114C203014093 @default.
- W2019644114 hasConceptScore W2019644114C2777385706 @default.
- W2019644114 hasConceptScore W2019644114C2778248108 @default.
- W2019644114 hasConceptScore W2019644114C2778453870 @default.
- W2019644114 hasConceptScore W2019644114C2779703530 @default.
- W2019644114 hasConceptScore W2019644114C2780007613 @default.
- W2019644114 hasConceptScore W2019644114C2780931953 @default.
- W2019644114 hasConceptScore W2019644114C28328180 @default.
- W2019644114 hasConceptScore W2019644114C71924100 @default.
- W2019644114 hasConceptScore W2019644114C86803240 @default.
- W2019644114 hasConceptScore W2019644114C95444343 @default.
- W2019644114 hasIssue "4" @default.
- W2019644114 hasLocation W20196441141 @default.
- W2019644114 hasLocation W20196441142 @default.
- W2019644114 hasOpenAccess W2019644114 @default.
- W2019644114 hasPrimaryLocation W20196441141 @default.
- W2019644114 hasRelatedWork W1807807041 @default.
- W2019644114 hasRelatedWork W1975791409 @default.
- W2019644114 hasRelatedWork W1989415625 @default.
- W2019644114 hasRelatedWork W2134304007 @default.
- W2019644114 hasRelatedWork W2412102303 @default.
- W2019644114 hasRelatedWork W2413538228 @default.
- W2019644114 hasRelatedWork W2414720610 @default.
- W2019644114 hasRelatedWork W2416888267 @default.
- W2019644114 hasRelatedWork W2417320181 @default.
- W2019644114 hasRelatedWork W2472644284 @default.
- W2019644114 hasVolume "19" @default.
- W2019644114 isParatext "false" @default.
- W2019644114 isRetracted "false" @default.
- W2019644114 magId "2019644114" @default.
- W2019644114 workType "article" @default.