Matches in SemOpenAlex for { <https://semopenalex.org/work/W2019655276> ?p ?o ?g. }
Showing items 1 to 71 of
71
with 100 items per page.
- W2019655276 abstract "ABSTRACT Previous studies have established that the IGFs are involved in oestrogen-induced uterine proliferation. IGF-binding proteins (IGFBPs) are present in most biological fluids and tissues and may modulate the actions of the IGFs. We examined uterine, hepatic and renal expression of the IGFBPs throughout the oestrous cycle and investigated the effects of oestradiol (OE 2 ) on IGFBP expression in ovariectomized (ovx) rats. Uterine expression of IGFBPs-1 and -3 showed a definite variation throughout the oestrous cycle with highest levels during dioestrus. In the liver and kidney the changes in IGFBP-1 and IGFBP-3 mRNA abundance were the opposite of those observed in the uterus, with the highest levels observed during oestrus. Administration of OE 2 to ovx rats decreased uterine IGFBP-3 mRNA and increased IGFBP-4 mRNA levels. In these rats there were no consistent changes in renal IGFBP-1 or IGFBP-3 mRNAs; however, a significant increase in IGFBP-4 mRNA was observed in this tissue, as in the uterus. In the liver an increase in IGFBP-1 mRNA and a decrease in IGFBP-3 mRNA levels were observed in rats treated with OE 2 . Despite changes in uterine, hepatic and renal IGFBP mRNA levels, no significant variation was seen in serum IGFBPs as determined by ligand blotting of sera. These data demonstrate that there is a cyclical variation in the expression of the IGFBPs in the uterus, kidney and liver, and that OE 2 is able to modulate differentially IGFBP expression in these tissues." @default.
- W2019655276 created "2016-06-24" @default.
- W2019655276 creator A5014997892 @default.
- W2019655276 creator A5024624574 @default.
- W2019655276 date "1994-08-01" @default.
- W2019655276 modified "2023-09-24" @default.
- W2019655276 title "Effects of oestrogen on rat uterine expression of insulin-like growth factor-binding proteins" @default.
- W2019655276 doi "https://doi.org/10.1677/jme.0.0130059" @default.
- W2019655276 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7528021" @default.
- W2019655276 hasPublicationYear "1994" @default.
- W2019655276 type Work @default.
- W2019655276 sameAs 2019655276 @default.
- W2019655276 citedByCount "34" @default.
- W2019655276 countsByYear W20196552762013 @default.
- W2019655276 countsByYear W20196552762014 @default.
- W2019655276 countsByYear W20196552762018 @default.
- W2019655276 crossrefType "journal-article" @default.
- W2019655276 hasAuthorship W2019655276A5014997892 @default.
- W2019655276 hasAuthorship W2019655276A5024624574 @default.
- W2019655276 hasConcept C104317684 @default.
- W2019655276 hasConcept C105580179 @default.
- W2019655276 hasConcept C126322002 @default.
- W2019655276 hasConcept C134018914 @default.
- W2019655276 hasConcept C170493617 @default.
- W2019655276 hasConcept C185592680 @default.
- W2019655276 hasConcept C1998276 @default.
- W2019655276 hasConcept C2775960820 @default.
- W2019655276 hasConcept C2777164284 @default.
- W2019655276 hasConcept C2779066055 @default.
- W2019655276 hasConcept C2780091579 @default.
- W2019655276 hasConcept C2780378035 @default.
- W2019655276 hasConcept C2780689927 @default.
- W2019655276 hasConcept C55493867 @default.
- W2019655276 hasConcept C71924100 @default.
- W2019655276 hasConcept C8264082 @default.
- W2019655276 hasConcept C86803240 @default.
- W2019655276 hasConceptScore W2019655276C104317684 @default.
- W2019655276 hasConceptScore W2019655276C105580179 @default.
- W2019655276 hasConceptScore W2019655276C126322002 @default.
- W2019655276 hasConceptScore W2019655276C134018914 @default.
- W2019655276 hasConceptScore W2019655276C170493617 @default.
- W2019655276 hasConceptScore W2019655276C185592680 @default.
- W2019655276 hasConceptScore W2019655276C1998276 @default.
- W2019655276 hasConceptScore W2019655276C2775960820 @default.
- W2019655276 hasConceptScore W2019655276C2777164284 @default.
- W2019655276 hasConceptScore W2019655276C2779066055 @default.
- W2019655276 hasConceptScore W2019655276C2780091579 @default.
- W2019655276 hasConceptScore W2019655276C2780378035 @default.
- W2019655276 hasConceptScore W2019655276C2780689927 @default.
- W2019655276 hasConceptScore W2019655276C55493867 @default.
- W2019655276 hasConceptScore W2019655276C71924100 @default.
- W2019655276 hasConceptScore W2019655276C8264082 @default.
- W2019655276 hasConceptScore W2019655276C86803240 @default.
- W2019655276 hasLocation W20196552761 @default.
- W2019655276 hasLocation W20196552762 @default.
- W2019655276 hasOpenAccess W2019655276 @default.
- W2019655276 hasPrimaryLocation W20196552761 @default.
- W2019655276 hasRelatedWork W1966656070 @default.
- W2019655276 hasRelatedWork W1987925690 @default.
- W2019655276 hasRelatedWork W2000907318 @default.
- W2019655276 hasRelatedWork W2014460450 @default.
- W2019655276 hasRelatedWork W2019655276 @default.
- W2019655276 hasRelatedWork W2024275708 @default.
- W2019655276 hasRelatedWork W2044134935 @default.
- W2019655276 hasRelatedWork W2047059589 @default.
- W2019655276 hasRelatedWork W2073168082 @default.
- W2019655276 hasRelatedWork W2104198153 @default.
- W2019655276 isParatext "false" @default.
- W2019655276 isRetracted "false" @default.
- W2019655276 magId "2019655276" @default.
- W2019655276 workType "article" @default.