Matches in SemOpenAlex for { <https://semopenalex.org/work/W2019656295> ?p ?o ?g. }
Showing items 1 to 91 of
91
with 100 items per page.
- W2019656295 endingPage "672" @default.
- W2019656295 startingPage "666" @default.
- W2019656295 abstract "Trichohyalin, a protein contained in granules in the cells of the hair-follicle inner root sheath and in the medulla of the hair shaft, has been purified previously from sheep hair bulbs and is also a major protein of filiform papillae of tongue epithelium. Polyclonal affinity-purified antibodies and a monoclonal antibody raised to purified pig tongue trichohyalin both stained the inner root sheath of hair follicles and the medulla of hair fibers and identified human trichohyalin as a single 220-kDa band on immunoblots of human hair bulb proteins. These antibodies were used to examine human epidermis by immunofluorescence and immunoblotting. The antibodies decorate granules in cells in the granular layer and stratum corneum of non-hair-bearing human skin, and immunoblots identify a protein in epidermis comigrating with trichohyalin from human hair and human tongue epithelium. Absorption of antibody to trichohyalin on a trichohyalin affinity column abrogated staining of the epidermis and the bands on the immunoblots. Trypsin-separated epidermis contained 220 and 160 kDa bands identified as trichohyalin, but epidermis shaved from skin and quickly frozen showed only a single 220-kDa band, indicating that the 160-kDa protein was generated by proteolysis. Double immunofluorescence for trichohyalin and filaggrin showed that some cells containing filaggrin also contain trichohyalin. These studies show that trichohyalin is not limited to hair and tongue but is present in isolated cells in the granular layer and stratum corneum of normal epidermis." @default.
- W2019656295 created "2016-06-24" @default.
- W2019656295 creator A5026660216 @default.
- W2019656295 creator A5029435674 @default.
- W2019656295 creator A5065805845 @default.
- W2019656295 date "1991-05-01" @default.
- W2019656295 modified "2023-09-26" @default.
- W2019656295 title "Trichohyalin: Presence in the Granular Layer and Stratum Corneum of Normal Human Epidermis" @default.
- W2019656295 cites W1548930741 @default.
- W2019656295 cites W2030522563 @default.
- W2019656295 cites W2038008546 @default.
- W2019656295 cites W2044453539 @default.
- W2019656295 cites W2061071314 @default.
- W2019656295 cites W2072466722 @default.
- W2019656295 cites W2076858319 @default.
- W2019656295 cites W2103304027 @default.
- W2019656295 cites W2104027941 @default.
- W2019656295 cites W2111817213 @default.
- W2019656295 cites W2125911728 @default.
- W2019656295 doi "https://doi.org/10.1111/1523-1747.ep12470590" @default.
- W2019656295 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1708794" @default.
- W2019656295 hasPublicationYear "1991" @default.
- W2019656295 type Work @default.
- W2019656295 sameAs 2019656295 @default.
- W2019656295 citedByCount "48" @default.
- W2019656295 countsByYear W20196562952012 @default.
- W2019656295 countsByYear W20196562952013 @default.
- W2019656295 countsByYear W20196562952014 @default.
- W2019656295 countsByYear W20196562952018 @default.
- W2019656295 countsByYear W20196562952019 @default.
- W2019656295 countsByYear W20196562952021 @default.
- W2019656295 crossrefType "journal-article" @default.
- W2019656295 hasAuthorship W2019656295A5026660216 @default.
- W2019656295 hasAuthorship W2019656295A5029435674 @default.
- W2019656295 hasAuthorship W2019656295A5065805845 @default.
- W2019656295 hasConcept C105702510 @default.
- W2019656295 hasConcept C151730666 @default.
- W2019656295 hasConcept C153911025 @default.
- W2019656295 hasConcept C169760540 @default.
- W2019656295 hasConcept C179927520 @default.
- W2019656295 hasConcept C2776458125 @default.
- W2019656295 hasConcept C2777216303 @default.
- W2019656295 hasConcept C2778370115 @default.
- W2019656295 hasConcept C2779185020 @default.
- W2019656295 hasConcept C2779652256 @default.
- W2019656295 hasConcept C2779688582 @default.
- W2019656295 hasConcept C2779922919 @default.
- W2019656295 hasConcept C2780680797 @default.
- W2019656295 hasConcept C54355233 @default.
- W2019656295 hasConcept C81241287 @default.
- W2019656295 hasConcept C86803240 @default.
- W2019656295 hasConcept C95444343 @default.
- W2019656295 hasConceptScore W2019656295C105702510 @default.
- W2019656295 hasConceptScore W2019656295C151730666 @default.
- W2019656295 hasConceptScore W2019656295C153911025 @default.
- W2019656295 hasConceptScore W2019656295C169760540 @default.
- W2019656295 hasConceptScore W2019656295C179927520 @default.
- W2019656295 hasConceptScore W2019656295C2776458125 @default.
- W2019656295 hasConceptScore W2019656295C2777216303 @default.
- W2019656295 hasConceptScore W2019656295C2778370115 @default.
- W2019656295 hasConceptScore W2019656295C2779185020 @default.
- W2019656295 hasConceptScore W2019656295C2779652256 @default.
- W2019656295 hasConceptScore W2019656295C2779688582 @default.
- W2019656295 hasConceptScore W2019656295C2779922919 @default.
- W2019656295 hasConceptScore W2019656295C2780680797 @default.
- W2019656295 hasConceptScore W2019656295C54355233 @default.
- W2019656295 hasConceptScore W2019656295C81241287 @default.
- W2019656295 hasConceptScore W2019656295C86803240 @default.
- W2019656295 hasConceptScore W2019656295C95444343 @default.
- W2019656295 hasIssue "5" @default.
- W2019656295 hasLocation W20196562951 @default.
- W2019656295 hasLocation W20196562952 @default.
- W2019656295 hasOpenAccess W2019656295 @default.
- W2019656295 hasPrimaryLocation W20196562951 @default.
- W2019656295 hasRelatedWork W1977940853 @default.
- W2019656295 hasRelatedWork W1980928141 @default.
- W2019656295 hasRelatedWork W2009945414 @default.
- W2019656295 hasRelatedWork W2019656295 @default.
- W2019656295 hasRelatedWork W2094338165 @default.
- W2019656295 hasRelatedWork W2965258500 @default.
- W2019656295 hasRelatedWork W2985418523 @default.
- W2019656295 hasRelatedWork W57485934 @default.
- W2019656295 hasRelatedWork W76289338 @default.
- W2019656295 hasRelatedWork W82391381 @default.
- W2019656295 hasVolume "96" @default.
- W2019656295 isParatext "false" @default.
- W2019656295 isRetracted "false" @default.
- W2019656295 magId "2019656295" @default.
- W2019656295 workType "article" @default.