Matches in SemOpenAlex for { <https://semopenalex.org/work/W2019668085> ?p ?o ?g. }
- W2019668085 endingPage "967" @default.
- W2019668085 startingPage "959" @default.
- W2019668085 abstract "Cardiac calsequestrin (Casq2) is the major Ca2+ binding protein in the sarcoplasmic reticulum, which is the principle Ca2+ storage organelle of cardiac muscle. During the last decade, experimental studies have provided new concepts on the role of Casq2 in the regulation of cardiac muscle Ca2+ handling. Furthermore, mutations in the gene encoding for cardiac calsequestrin, CASQ2, cause a rare but severe form of catecholaminergic polymorphic ventricular tachycardia (CPVT). Here, we review the physiology of Casq2 in cardiac Ca2+ handling and discuss pathophysiological mechanisms that lead to CPVT caused by CASQ2 mutations. We also describe the clinical aspects of CPVT and provide an update of its contemporary clinical management." @default.
- W2019668085 created "2016-06-24" @default.
- W2019668085 creator A5017112672 @default.
- W2019668085 creator A5064477997 @default.
- W2019668085 creator A5080126593 @default.
- W2019668085 date "2012-03-16" @default.
- W2019668085 modified "2023-10-02" @default.
- W2019668085 title "Calsequestrin Mutations and Catecholaminergic Polymorphic Ventricular Tachycardia" @default.
- W2019668085 cites W1481469889 @default.
- W2019668085 cites W1558794683 @default.
- W2019668085 cites W1576981355 @default.
- W2019668085 cites W1603752295 @default.
- W2019668085 cites W1963984360 @default.
- W2019668085 cites W1965223903 @default.
- W2019668085 cites W1967658895 @default.
- W2019668085 cites W1971696434 @default.
- W2019668085 cites W1971833900 @default.
- W2019668085 cites W1979776094 @default.
- W2019668085 cites W1986652655 @default.
- W2019668085 cites W1988998632 @default.
- W2019668085 cites W1989553550 @default.
- W2019668085 cites W1993190948 @default.
- W2019668085 cites W1994681182 @default.
- W2019668085 cites W1998491240 @default.
- W2019668085 cites W1999093802 @default.
- W2019668085 cites W2002616364 @default.
- W2019668085 cites W2003290962 @default.
- W2019668085 cites W2012531906 @default.
- W2019668085 cites W2019810107 @default.
- W2019668085 cites W2023609755 @default.
- W2019668085 cites W2031973792 @default.
- W2019668085 cites W2035699845 @default.
- W2019668085 cites W2040794750 @default.
- W2019668085 cites W2041410896 @default.
- W2019668085 cites W2048022581 @default.
- W2019668085 cites W2050824263 @default.
- W2019668085 cites W2051165347 @default.
- W2019668085 cites W2053330560 @default.
- W2019668085 cites W2055928084 @default.
- W2019668085 cites W2059063609 @default.
- W2019668085 cites W2059839559 @default.
- W2019668085 cites W2063994440 @default.
- W2019668085 cites W2064117137 @default.
- W2019668085 cites W2067254948 @default.
- W2019668085 cites W2070009182 @default.
- W2019668085 cites W2071234680 @default.
- W2019668085 cites W2072499242 @default.
- W2019668085 cites W2073352540 @default.
- W2019668085 cites W2073472013 @default.
- W2019668085 cites W2074373626 @default.
- W2019668085 cites W2074777877 @default.
- W2019668085 cites W2075043037 @default.
- W2019668085 cites W2075333692 @default.
- W2019668085 cites W2080955459 @default.
- W2019668085 cites W2081524260 @default.
- W2019668085 cites W2090820454 @default.
- W2019668085 cites W2095077534 @default.
- W2019668085 cites W2095152173 @default.
- W2019668085 cites W2097312037 @default.
- W2019668085 cites W2100626082 @default.
- W2019668085 cites W2108325543 @default.
- W2019668085 cites W2109748617 @default.
- W2019668085 cites W2111394029 @default.
- W2019668085 cites W2114329647 @default.
- W2019668085 cites W2114454864 @default.
- W2019668085 cites W2120733956 @default.
- W2019668085 cites W2124053445 @default.
- W2019668085 cites W2126385122 @default.
- W2019668085 cites W2129115366 @default.
- W2019668085 cites W2132856292 @default.
- W2019668085 cites W2138323127 @default.
- W2019668085 cites W2138788197 @default.
- W2019668085 cites W2140661076 @default.
- W2019668085 cites W2144152000 @default.
- W2019668085 cites W2146053159 @default.
- W2019668085 cites W2147515006 @default.
- W2019668085 cites W2150075279 @default.
- W2019668085 cites W2153073011 @default.
- W2019668085 cites W2159958920 @default.
- W2019668085 cites W2163547302 @default.
- W2019668085 cites W2163907934 @default.
- W2019668085 cites W2166519632 @default.
- W2019668085 cites W2168013049 @default.
- W2019668085 cites W2226437153 @default.
- W2019668085 cites W2564375465 @default.
- W2019668085 cites W3021289375 @default.
- W2019668085 cites W30756424 @default.
- W2019668085 doi "https://doi.org/10.1007/s00246-012-0256-1" @default.
- W2019668085 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3393815" @default.
- W2019668085 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22421959" @default.
- W2019668085 hasPublicationYear "2012" @default.
- W2019668085 type Work @default.
- W2019668085 sameAs 2019668085 @default.
- W2019668085 citedByCount "45" @default.
- W2019668085 countsByYear W20196680852012 @default.
- W2019668085 countsByYear W20196680852013 @default.
- W2019668085 countsByYear W20196680852014 @default.
- W2019668085 countsByYear W20196680852015 @default.