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• W2019689572 abstract "Objective: To determine serum levels of vascular endothelial growth factor (VEGF) and evaluate their capacity to serve as a marker for the diagnosis of ectopic pregnancy (EP).Design: Prospective, case-controlled study.Setting: A tertiary care center.Patient(s): Twenty women with EP, 10 women with normal intrauterine pregnancy, and 10 women with abnormal intrauterine pregnancy, all at comparable stages of gestation.Intervention(s): Serum samples were obtained from all women.Main Outcome Measure(s): All samples were analyzed for VEGF, progesterone, and β-hCG by specific methods.Result(s): Women with EP had higher serum levels of VEGF than women with normal intrauterine pregnancy and women with abnormal intrauterine pregnancy (median levels, 226.8 pg/mL, 24.4 pg/mL, and 59.4 pg/mL, respectively). With a cutoff level of 200 pg/mL, serum VEGF could distinguish intrauterine from extrauterine pregnancy with a sensitivity of 60%, specificity of 90%, and positive predictive value of 86%.Conclusion(s): The increased serum VEGF levels in women with EP may facilitate this challenging diagnosis and reduce maternal morbidity and mortality." @default.
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• W2019689572 date "1999-12-01" @default.
• W2019689572 modified "2023-10-17" @default.
• W2019689572 title "Levels of vascular endothelial growth factor are elevated in patients with ectopic pregnancy: is this a novel marker?" @default.
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• W2019689572 doi "https://doi.org/10.1016/s0015-0282(99)00417-3" @default.
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