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Matches in SemOpenAlex for { <https://semopenalex.org/work/W2019691808> ?p ?o ?g. }

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• W2019691808 abstract "Epidermal growth factor (EGF) has been noted to stimulate proliferation of a variety of normal and malignant cells including those of human breast epithelium. We report here that MDA-468, a human breast cancer cell line with a very high number of EGF receptors, is growth-inhibited at EGF concentrations that stimulate most other cells. The basis for the elevated receptor level is EGF receptor gene amplification and over-expression. An MDA-468 clone selected for resistance to EGF-induced growth inhibition shows a number of receptors within the normal range. The results are discussed in relation to a threshold model for EGF-induced growth inhibition." @default.
• W2019691808 created "2016-06-24" @default.
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• W2019691808 date "1985-04-01" @default.
• W2019691808 modified "2023-10-18" @default.
• W2019691808 title "MDA-468, a human breast cancer cell line with a high number of epidermal growth factor (EGF) receptors, has an amplified EGF receptor gene and is growth inhibited by EGF" @default.
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• W2019691808 doi "https://doi.org/10.1016/0006-291x(85)90131-7" @default.
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