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• W2019691887 abstract "E2F transcription factor 3 (E2F3), a member of the E2F transcription factor family and a member of the genes involved in the regulation of cell cycle, is an oncogene with strong proliferative potential. E2F3 is involved in many processes and plays important roles in the development of several types of cancer, while its relationship with prognosis in hepatocellular carcinoma (HCC) has yet to be reported. In the present study, based on 4 independent microarray data sets which covered 385 cases of HCC and 327 cases of normal livers retrieved from the Oncomine database, we demonstrated that E2F3 was upregulated at least 1.5-fold and on average 2.3-fold in HCC when compared with normal controls. Comprehensive bioinformatics analysis consisting of protein-protein interaction, gene co-occurrence, microRNA-mRNA interaction and biological process annotation indicated that E2F3 interacted with a large number of genes, proteins and microRNAs which were all associated with poor prognosis in patients with HCC and other types of cancer, suggesting that E2F3 may also serve as a biomarker for poor prognosis. Taken together, for the first time, we show that the overexpression of E2F3 may be associated with unfavorable prognosis in HCC." @default.
• W2019691887 created "2016-06-24" @default.
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• W2019691887 date "2014-01-08" @default.
• W2019691887 modified "2023-09-30" @default.
• W2019691887 title "Upregulation of E2F transcription factor 3 is associated with poor prognosis in hepatocellular carcinoma" @default.
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• W2019691887 cites W1977918192 @default.
• W2019691887 cites W1981989535 @default.
• W2019691887 cites W1985055097 @default.
• W2019691887 cites W1987097208 @default.
• W2019691887 cites W1988092897 @default.
• W2019691887 cites W1991603403 @default.
• W2019691887 cites W1991896299 @default.
• W2019691887 cites W1992621857 @default.
• W2019691887 cites W1992917818 @default.
• W2019691887 cites W1993749140 @default.
• W2019691887 cites W1993831544 @default.
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• W2019691887 cites W2006088932 @default.
• W2019691887 cites W2008078491 @default.
• W2019691887 cites W2014796515 @default.
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• W2019691887 cites W2034744358 @default.
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• W2019691887 doi "https://doi.org/10.3892/or.2014.2968" @default.
• W2019691887 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24402082" @default.
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