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• W2019695716 abstract "Peripheral benzodiazepine receptors (PBR) may have a role in epilepsy and in mediating antiepileptic drug effects. Since PBR in blood mononuclear cells may be acted on by anticonvulsant drugs, we investigated possible modifications of these receptors in newly diagnosed patients, before and after antiepileptic treatment and in drug-resistant epileptic patients. A significantly lower receptor density, with no difference in affinity, was observed in drug-resistant patients, compared to newly diagnosed patients and to normal age-related controls. We suggest the possible use of PBR as a peripheral marker of drug response." @default.
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• W2019695716 date "1997-06-01" @default.
• W2019695716 modified "2023-09-27" @default.
• W2019695716 title "Decreased density of lymphocyte benzodiazepine receptors in drug-resistant epileptic patients" @default.
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• W2019695716 doi "https://doi.org/10.1016/s0920-1211(97)01035-8" @default.
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