FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2019705493> ?p ?o ?g. }

• W2019705493 endingPage "215" @default.
• W2019705493 startingPage "212" @default.
• W2019705493 abstract "Several variants of the catechol-O-methyltransferase (COMT) gene have recently been linked to pain sensitivity. In the present study, electrophysiological field potential recordings from the dorsal horn in rats were used to examine the spinal effect of reduced COMT activity. The data demonstrated that 30 mg/kg of the COMT inhibitor OR 486 reduced spinal nociceptive responses to painful stimuli (p ≤ 0.01, OR 486 vs. vehicle) and attenuated the expression of spinal long-term potentiation (LTP), an often studied model for central sensitization (p ≤ 0.01, HFS vs. HFS + OR 486). Our findings suggest that low COMT activity may have an antinociceptive effect in the spinal cord." @default.
• W2019705493 created "2016-06-24" @default.
• W2019705493 creator A5006685576 @default.
• W2019705493 creator A5007708150 @default.
• W2019705493 creator A5016579408 @default.
• W2019705493 creator A5043108793 @default.
• W2019705493 date "2010-04-01" @default.
• W2019705493 modified "2023-10-17" @default.
• W2019705493 title "Catechol-O-methyltransferase (COMT) inhibition reduces spinal nociceptive activity" @default.
• W2019705493 cites W1483867462 @default.
• W2019705493 cites W1575333601 @default.
• W2019705493 cites W1961384091 @default.
• W2019705493 cites W1964268043 @default.
• W2019705493 cites W1964941501 @default.
• W2019705493 cites W1980349142 @default.
• W2019705493 cites W1999864181 @default.
• W2019705493 cites W2000129228 @default.
• W2019705493 cites W2000565838 @default.
• W2019705493 cites W2016124588 @default.
• W2019705493 cites W2031807874 @default.
• W2019705493 cites W2040493240 @default.
• W2019705493 cites W2050194934 @default.
• W2019705493 cites W2053364621 @default.
• W2019705493 cites W2067283365 @default.
• W2019705493 cites W2084424517 @default.
• W2019705493 cites W2089202291 @default.
• W2019705493 cites W2091655648 @default.
• W2019705493 cites W2093421716 @default.
• W2019705493 cites W2134814434 @default.
• W2019705493 cites W2141678708 @default.
• W2019705493 cites W2146481987 @default.
• W2019705493 cites W4313371117 @default.
• W2019705493 doi "https://doi.org/10.1016/j.neulet.2010.02.049" @default.
• W2019705493 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20219633" @default.
• W2019705493 hasPublicationYear "2010" @default.
• W2019705493 type Work @default.
• W2019705493 sameAs 2019705493 @default.
• W2019705493 citedByCount "21" @default.
• W2019705493 countsByYear W20197054932012 @default.
• W2019705493 countsByYear W20197054932013 @default.
• W2019705493 countsByYear W20197054932015 @default.
• W2019705493 countsByYear W20197054932016 @default.
• W2019705493 countsByYear W20197054932017 @default.
• W2019705493 countsByYear W20197054932019 @default.
• W2019705493 countsByYear W20197054932020 @default.
• W2019705493 countsByYear W20197054932021 @default.
• W2019705493 countsByYear W20197054932022 @default.
• W2019705493 crossrefType "journal-article" @default.
• W2019705493 hasAuthorship W2019705493A5006685576 @default.
• W2019705493 hasAuthorship W2019705493A5007708150 @default.
• W2019705493 hasAuthorship W2019705493A5016579408 @default.
• W2019705493 hasAuthorship W2019705493A5043108793 @default.
• W2019705493 hasConcept C104317684 @default.
• W2019705493 hasConcept C126322002 @default.
• W2019705493 hasConcept C15490471 @default.
• W2019705493 hasConcept C15744967 @default.
• W2019705493 hasConcept C169760540 @default.
• W2019705493 hasConcept C170493617 @default.
• W2019705493 hasConcept C180754005 @default.
• W2019705493 hasConcept C185263204 @default.
• W2019705493 hasConcept C185361966 @default.
• W2019705493 hasConcept C185592680 @default.
• W2019705493 hasConcept C25274449 @default.
• W2019705493 hasConcept C2776217527 @default.
• W2019705493 hasConcept C2779245659 @default.
• W2019705493 hasConcept C2780775167 @default.
• W2019705493 hasConcept C529278444 @default.
• W2019705493 hasConcept C55493867 @default.
• W2019705493 hasConcept C71924100 @default.
• W2019705493 hasConcept C98274493 @default.
• W2019705493 hasConceptScore W2019705493C104317684 @default.
• W2019705493 hasConceptScore W2019705493C126322002 @default.
• W2019705493 hasConceptScore W2019705493C15490471 @default.
• W2019705493 hasConceptScore W2019705493C15744967 @default.
• W2019705493 hasConceptScore W2019705493C169760540 @default.
• W2019705493 hasConceptScore W2019705493C170493617 @default.
• W2019705493 hasConceptScore W2019705493C180754005 @default.
• W2019705493 hasConceptScore W2019705493C185263204 @default.
• W2019705493 hasConceptScore W2019705493C185361966 @default.
• W2019705493 hasConceptScore W2019705493C185592680 @default.
• W2019705493 hasConceptScore W2019705493C25274449 @default.
• W2019705493 hasConceptScore W2019705493C2776217527 @default.
• W2019705493 hasConceptScore W2019705493C2779245659 @default.
• W2019705493 hasConceptScore W2019705493C2780775167 @default.
• W2019705493 hasConceptScore W2019705493C529278444 @default.
• W2019705493 hasConceptScore W2019705493C55493867 @default.
• W2019705493 hasConceptScore W2019705493C71924100 @default.
• W2019705493 hasConceptScore W2019705493C98274493 @default.
• W2019705493 hasIssue "3" @default.
• W2019705493 hasLocation W20197054931 @default.
• W2019705493 hasLocation W20197054932 @default.
• W2019705493 hasOpenAccess W2019705493 @default.
• W2019705493 hasPrimaryLocation W20197054931 @default.
• W2019705493 hasRelatedWork W1511481184 @default.
• W2019705493 hasRelatedWork W1526038313 @default.
• W2019705493 hasRelatedWork W1973434522 @default.
• W2019705493 hasRelatedWork W1976105490 @default.
• W2019705493 hasRelatedWork W2006037730 @default.

• next