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- W2019724054 startingPage "37" @default.
- W2019724054 abstract "The aim of this study was to evaluate the cytotoxic effects of five different resin-based root canal sealers: EndoREZ, Epiphany SE, EZ-Fill, MMSeal and AHPlus. Set materials were extracted in culture medium and cytotoxicity was determined in two cell lines, human osteosarcoma cell line (Saos-2) and mouse skin fibroblast cells (L929). The cells were incubated in contact with elutes for 24 h. The cell mitochondrial activity was evaluated by the methylthiazole tetrazolium assay. Results with demonstrated that all sealers showed a reduced vital cell number in comparison with the control group (P MMSeal (44%) = Epiphany SE (46.2 %). For Saos-2 cells revealed that cell survival with extracts of EndoREZ, Epiphany SE, EZ-Fill, MMSeal and AHPlus was 33.9%, 32.9 %, 33.1%, 35.3% and 34.6%, respectively, all tested sealers showed moderate cytotoxicity. Based on the results obtained from the present study, all tested resin-based sealers appear to show toxicity potential to both cells in spite of different toxicity degrees. Therefore, better sealers need to be developed with acceptable biological properties for root canal filling." @default.
- W2019724054 created "2016-06-24" @default.
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- W2019724054 date "2013-05-01" @default.
- W2019724054 modified "2023-10-17" @default.
- W2019724054 title "Effects of five different resin-based sealers on L929 and Saos-2 cell viability" @default.
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- W2019724054 doi "https://doi.org/10.4103/wkmp-0028.117443" @default.
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