FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2019792136> ?p ?o ?g. }

• W2019792136 endingPage "335" @default.
• W2019792136 startingPage "329" @default.
• W2019792136 abstract "Summary: Time trends in the prevalence of drug resistance to antiretroviral therapy (ART) in pregnant women have not been studied. Treatment and prophylactic efficacy could be compromised by drug-resistant HIV strains. We conducted a repeated cross-sectional study of antiretroviral resistance mutations to nucleoside reverse transcriptase inhibitors (NRTIs) and nonnucleoside reverse transcriptase inhibitors (NNRTIs) and of major mutations to protease inhibitors (PIs) in virus isolates from 300 HIV-infected pregnant women in New York City from 1991 to early 2001. The overall prevalence of mutations for NRTIs from 1991 to early 2001 was higher for ART-experienced (25.6% [95% confidence interval (CI): 19.1% to 32.1%]) than ART-naive (8.6% [95% CI: 3.7% to 13.4%]) mothers (P < 0.002). For NNRTIs, the overall prevalence of mutations was somewhat higher among ART-experienced (5.8% [95% CI: 2.3% to 9.3%]) versus ART-naive (1.6% [95% CI: 0% to 3.7%]) women (P = 0.06), and increased over time for ART-naive women (0%-7.4%; P = 0.03) and ART-experienced women (0%-19.4%; P = 0.0002). The prevalence of PI-associated mutations was also higher overall among ART-experienced mothers (5.8% [95% CI: 2.3% to 9.3%] vs. 1.6% [95% CI: 0% to 3.7%]; P = 0.06), with increases over time seen for ART-naive women (0%-7.4%; P = 0.03) and ART-experienced women (0%-16.1%; P = 0.0008). The increasing prevalence of drug resistance in pregnant women, including those who are drug-naive, underscores the necessity for resistance testing to guide treatment to achieve suppression of the mother's virus." @default.
• W2019792136 created "2016-06-24" @default.
• W2019792136 creator A5007442463 @default.
• W2019792136 creator A5007707615 @default.
• W2019792136 creator A5017451805 @default.
• W2019792136 creator A5030681177 @default.
• W2019792136 creator A5039611599 @default.
• W2019792136 date "2007-03-01" @default.
• W2019792136 modified "2023-09-27" @default.
• W2019792136 title "Time Trends for HIV-1 Antiretroviral Resistance Among Antiretroviral-Experienced and Naive Pregnant Women in New York City During 1991 to Early 2001" @default.
• W2019792136 cites W1894438159 @default.
• W2019792136 cites W1970663962 @default.
• W2019792136 cites W1973074600 @default.
• W2019792136 cites W1978003867 @default.
• W2019792136 cites W2001385376 @default.
• W2019792136 cites W2005648381 @default.
• W2019792136 cites W2006389041 @default.
• W2019792136 cites W2014746968 @default.
• W2019792136 cites W2030846679 @default.
• W2019792136 cites W2043176798 @default.
• W2019792136 cites W2047734031 @default.
• W2019792136 cites W2051939247 @default.
• W2019792136 cites W2055312332 @default.
• W2019792136 cites W2060586786 @default.
• W2019792136 cites W2079485880 @default.
• W2019792136 cites W2086783015 @default.
• W2019792136 cites W2116053826 @default.
• W2019792136 cites W2120255324 @default.
• W2019792136 cites W2122284754 @default.
• W2019792136 cites W2122858451 @default.
• W2019792136 cites W2128327031 @default.
• W2019792136 cites W2141253154 @default.
• W2019792136 cites W2155331329 @default.
• W2019792136 cites W2161953003 @default.
• W2019792136 cites W2167049427 @default.
• W2019792136 cites W2328466122 @default.
• W2019792136 cites W4232519590 @default.
• W2019792136 doi "https://doi.org/10.1097/qai.0b013e31802f1296" @default.
• W2019792136 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17179768" @default.
• W2019792136 hasPublicationYear "2007" @default.
• W2019792136 type Work @default.
• W2019792136 sameAs 2019792136 @default.
• W2019792136 citedByCount "18" @default.
• W2019792136 countsByYear W20197921362012 @default.
• W2019792136 countsByYear W20197921362013 @default.
• W2019792136 crossrefType "journal-article" @default.
• W2019792136 hasAuthorship W2019792136A5007442463 @default.
• W2019792136 hasAuthorship W2019792136A5007707615 @default.
• W2019792136 hasAuthorship W2019792136A5017451805 @default.
• W2019792136 hasAuthorship W2019792136A5030681177 @default.
• W2019792136 hasAuthorship W2019792136A5039611599 @default.
• W2019792136 hasBestOaLocation W20197921361 @default.
• W2019792136 hasConcept C114851261 @default.
• W2019792136 hasConcept C126322002 @default.
• W2019792136 hasConcept C142462285 @default.
• W2019792136 hasConcept C159047783 @default.
• W2019792136 hasConcept C205545832 @default.
• W2019792136 hasConcept C2777090001 @default.
• W2019792136 hasConcept C2777351918 @default.
• W2019792136 hasConcept C2778451633 @default.
• W2019792136 hasConcept C2779234561 @default.
• W2019792136 hasConcept C2780035454 @default.
• W2019792136 hasConcept C2781143361 @default.
• W2019792136 hasConcept C2909970146 @default.
• W2019792136 hasConcept C2993143319 @default.
• W2019792136 hasConcept C3013748606 @default.
• W2019792136 hasConcept C44249647 @default.
• W2019792136 hasConcept C54355233 @default.
• W2019792136 hasConcept C71924100 @default.
• W2019792136 hasConcept C86803240 @default.
• W2019792136 hasConcept C89423630 @default.
• W2019792136 hasConcept C98274493 @default.
• W2019792136 hasConceptScore W2019792136C114851261 @default.
• W2019792136 hasConceptScore W2019792136C126322002 @default.
• W2019792136 hasConceptScore W2019792136C142462285 @default.
• W2019792136 hasConceptScore W2019792136C159047783 @default.
• W2019792136 hasConceptScore W2019792136C205545832 @default.
• W2019792136 hasConceptScore W2019792136C2777090001 @default.
• W2019792136 hasConceptScore W2019792136C2777351918 @default.
• W2019792136 hasConceptScore W2019792136C2778451633 @default.
• W2019792136 hasConceptScore W2019792136C2779234561 @default.
• W2019792136 hasConceptScore W2019792136C2780035454 @default.
• W2019792136 hasConceptScore W2019792136C2781143361 @default.
• W2019792136 hasConceptScore W2019792136C2909970146 @default.
• W2019792136 hasConceptScore W2019792136C2993143319 @default.
• W2019792136 hasConceptScore W2019792136C3013748606 @default.
• W2019792136 hasConceptScore W2019792136C44249647 @default.
• W2019792136 hasConceptScore W2019792136C54355233 @default.
• W2019792136 hasConceptScore W2019792136C71924100 @default.
• W2019792136 hasConceptScore W2019792136C86803240 @default.
• W2019792136 hasConceptScore W2019792136C89423630 @default.
• W2019792136 hasConceptScore W2019792136C98274493 @default.
• W2019792136 hasIssue "3" @default.
• W2019792136 hasLocation W20197921361 @default.
• W2019792136 hasLocation W20197921362 @default.
• W2019792136 hasOpenAccess W2019792136 @default.
• W2019792136 hasPrimaryLocation W20197921361 @default.
• W2019792136 hasRelatedWork W151053760 @default.

• next