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- W2019801876 abstract "The nucleic acid content in Candida utilis was autolytically reduced only after previous lyophilization of yeast cells or pretreatment of the cells with ethyl acetate. These pretreatments provided a sufficient permeability of the cell membrane system and thus enabled a reduction of the nucleic acid content. While deep freezing of the cells (−35 °C) had no positive effect on the degradation of nucleic acids, lyophilization of yeast cells led to a 75% decrease of the nucleic acid content. Furthermore, a 55% reduction of the nucleic acid content was proceeded without a concomitant loss of proteins. Similar results were obtained by using ethyl acetate." @default.
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- W2019801876 date "1990-01-01" @default.
- W2019801876 modified "2023-09-27" @default.
- W2019801876 title "Autolytic reduction of the nucleic acid content inCandida utilis" @default.
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- W2019801876 doi "https://doi.org/10.1002/jobm.3620300508" @default.
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