Matches in SemOpenAlex for { <https://semopenalex.org/work/W2019804943> ?p ?o ?g. }
Showing items 1 to 76 of
76
with 100 items per page.
- W2019804943 endingPage "250" @default.
- W2019804943 startingPage "250" @default.
- W2019804943 abstract "The hypothalamic neuropeptides hypocretins (orexins) play a crucial role in the stability of arousal and alertness. Recent data have raised the hypothesis that hypocretin neurons are also part of the circuitries that mediate the hypothalamic stress response. In particular, we have recently demonstrated that corticotrophin-releasing factor (CRF)-immunoreactive terminals make direct synaptic contacts with hypocretin-expressing neurons and that numerous hypocretinergic neurons express the CRF-R1/2 receptors. Furthermore, CRF excites hypocretinergic cells ex vivo through CRF-R1 receptors. Activation of hypocretinergic neurons in response to acute stress is severely impaired in CRF-R1 knockout mice. Moreover, the stress response is impaired in hypocretin-deficient mice. We propose that upon stressor stimuli, CRF stimulates the release of hypocretins, and this circuit contributes to activation and maintenance of arousal associated with the stress response and addiction." @default.
- W2019804943 created "2016-06-24" @default.
- W2019804943 creator A5017686183 @default.
- W2019804943 creator A5053416972 @default.
- W2019804943 creator A5055709520 @default.
- W2019804943 creator A5071154443 @default.
- W2019804943 date "2005-01-01" @default.
- W2019804943 modified "2023-09-24" @default.
- W2019804943 title "The Corticotropin-Releasing Factor-Hypocretin Connection: Implications in Stress Response and Addiction" @default.
- W2019804943 doi "https://doi.org/10.1358/dnp.2005.18.4.908659" @default.
- W2019804943 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16034481" @default.
- W2019804943 hasPublicationYear "2005" @default.
- W2019804943 type Work @default.
- W2019804943 sameAs 2019804943 @default.
- W2019804943 citedByCount "30" @default.
- W2019804943 countsByYear W20198049432013 @default.
- W2019804943 countsByYear W20198049432014 @default.
- W2019804943 countsByYear W20198049432015 @default.
- W2019804943 countsByYear W20198049432016 @default.
- W2019804943 countsByYear W20198049432018 @default.
- W2019804943 countsByYear W20198049432019 @default.
- W2019804943 countsByYear W20198049432020 @default.
- W2019804943 countsByYear W20198049432023 @default.
- W2019804943 crossrefType "journal-article" @default.
- W2019804943 hasAuthorship W2019804943A5017686183 @default.
- W2019804943 hasAuthorship W2019804943A5053416972 @default.
- W2019804943 hasAuthorship W2019804943A5055709520 @default.
- W2019804943 hasAuthorship W2019804943A5071154443 @default.
- W2019804943 hasConcept C118303440 @default.
- W2019804943 hasConcept C118552586 @default.
- W2019804943 hasConcept C125370674 @default.
- W2019804943 hasConcept C126322002 @default.
- W2019804943 hasConcept C134018914 @default.
- W2019804943 hasConcept C15744967 @default.
- W2019804943 hasConcept C169760540 @default.
- W2019804943 hasConcept C170493617 @default.
- W2019804943 hasConcept C182704531 @default.
- W2019804943 hasConcept C200678441 @default.
- W2019804943 hasConcept C36951298 @default.
- W2019804943 hasConcept C48856860 @default.
- W2019804943 hasConcept C71924100 @default.
- W2019804943 hasConceptScore W2019804943C118303440 @default.
- W2019804943 hasConceptScore W2019804943C118552586 @default.
- W2019804943 hasConceptScore W2019804943C125370674 @default.
- W2019804943 hasConceptScore W2019804943C126322002 @default.
- W2019804943 hasConceptScore W2019804943C134018914 @default.
- W2019804943 hasConceptScore W2019804943C15744967 @default.
- W2019804943 hasConceptScore W2019804943C169760540 @default.
- W2019804943 hasConceptScore W2019804943C170493617 @default.
- W2019804943 hasConceptScore W2019804943C182704531 @default.
- W2019804943 hasConceptScore W2019804943C200678441 @default.
- W2019804943 hasConceptScore W2019804943C36951298 @default.
- W2019804943 hasConceptScore W2019804943C48856860 @default.
- W2019804943 hasConceptScore W2019804943C71924100 @default.
- W2019804943 hasIssue "4" @default.
- W2019804943 hasLocation W20198049431 @default.
- W2019804943 hasLocation W20198049432 @default.
- W2019804943 hasOpenAccess W2019804943 @default.
- W2019804943 hasPrimaryLocation W20198049431 @default.
- W2019804943 hasRelatedWork W1577371918 @default.
- W2019804943 hasRelatedWork W1996846474 @default.
- W2019804943 hasRelatedWork W2018368842 @default.
- W2019804943 hasRelatedWork W2033472167 @default.
- W2019804943 hasRelatedWork W2034583712 @default.
- W2019804943 hasRelatedWork W2063619316 @default.
- W2019804943 hasRelatedWork W2114765598 @default.
- W2019804943 hasRelatedWork W2169225653 @default.
- W2019804943 hasRelatedWork W2312865257 @default.
- W2019804943 hasRelatedWork W2414846389 @default.
- W2019804943 hasVolume "18" @default.
- W2019804943 isParatext "false" @default.
- W2019804943 isRetracted "false" @default.
- W2019804943 magId "2019804943" @default.
- W2019804943 workType "article" @default.